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Prolonged linezolid therapy induces progressive mitochondrial dysfunction in human peripheral blood mononuclear cells.

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Title: Prolonged linezolid therapy induces progressive mitochondrial dysfunction in human peripheral blood mononuclear cells.
Authors: Martínez-Guitián M; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain., Cajade-Pascual F; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain.; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain., Castro-Fernández DC; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain., Cuartero-Martínez A; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain., Nogueiras R; CIMUS, University of Santiago de Compostela- Health Research Institute of Santiago de Compostela, Santiago de Compostela, Galician, 15782, Spain.; Galician Agency of Innovation (GAIN), Xunta de Galicia, Santiago de Compostela, Spain., Fernández-Castro I; Internal Medicine Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain., Molinos-Castro S; Internal Medicine Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain., Ortea I; Proteomic Department, Center for Research in Nanomaterials and Nanotechnology (CINN-CSIC), Health Research Institute of Principado de Asturias (ISPA), Oviedo, Spain., Zarra-Ferro I; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain., González-Barcia M; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain.; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain., Fernández-Ferreiro A; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain. anxordes@gmail.com.; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain. anxordes@gmail.com., Mondelo-García C; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain. crismondelo1@gmail.com.; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain. crismondelo1@gmail.com.
Source: Journal of translational medicine [J Transl Med] 2026 Jun 09; Vol. 24 (1). Date of Electronic Publication: 2026 Jun 09.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Prolonged linezolid therapy induces progressive mitochondrial dysfunction in human peripheral blood mononuclear cells.
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  Data: <searchLink fieldCode="AU" term="%22Martínez-Guitián+M%22">Martínez-Guitián M</searchLink>; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain.<br /><searchLink fieldCode="AU" term="%22Cajade-Pascual+F%22">Cajade-Pascual F</searchLink>; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain.; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain.<br /><searchLink fieldCode="AU" term="%22Castro-Fernández+DC%22">Castro-Fernández DC</searchLink>; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain.<br /><searchLink fieldCode="AU" term="%22Cuartero-Martínez+A%22">Cuartero-Martínez A</searchLink>; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain.<br /><searchLink fieldCode="AU" term="%22Nogueiras+R%22">Nogueiras R</searchLink>; CIMUS, University of Santiago de Compostela- Health Research Institute of Santiago de Compostela, Santiago de Compostela, Galician, 15782, Spain.; Galician Agency of Innovation (GAIN), Xunta de Galicia, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández-Castro+I%22">Fernández-Castro I</searchLink>; Internal Medicine Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain.<br /><searchLink fieldCode="AU" term="%22Molinos-Castro+S%22">Molinos-Castro S</searchLink>; Internal Medicine Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain.<br /><searchLink fieldCode="AU" term="%22Ortea+I%22">Ortea I</searchLink>; Proteomic Department, Center for Research in Nanomaterials and Nanotechnology (CINN-CSIC), Health Research Institute of Principado de Asturias (ISPA), Oviedo, Spain.<br /><searchLink fieldCode="AU" term="%22Zarra-Ferro+I%22">Zarra-Ferro I</searchLink>; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain.<br /><searchLink fieldCode="AU" term="%22González-Barcia+M%22">González-Barcia M</searchLink>; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain.; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández-Ferreiro+A%22">Fernández-Ferreiro A</searchLink>; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain. anxordes@gmail.com.; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain. anxordes@gmail.com.<br /><searchLink fieldCode="AU" term="%22Mondelo-García+C%22">Mondelo-García C</searchLink>; FarmaCHUSLab, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain. crismondelo1@gmail.com.; Pharmacy Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, 15706, Spain. crismondelo1@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Jun 09; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Jun 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 09
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