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Serum cytokine profiling reveals CXCL10 (IP-10) as a major predictor of severe COVID-19 outcomes in hospitalized patients during the first pandemic wave in Italy.

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Title: Serum cytokine profiling reveals CXCL10 (IP-10) as a major predictor of severe COVID-19 outcomes in hospitalized patients during the first pandemic wave in Italy.
Authors: Muglia A; National PhD Programme in One Health approaches to infectious diseases and life science research, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Petrone D; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Schiavoni I; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Santinelli L; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy., Leone P; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Bella A; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., d'Ettorre G; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy., Alessandri F; Department of Anaesthesia and Intensive Care, Sapienza University of Rome, Rome, Italy., Palamara AT; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Mastroianni CM; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy., Stefanelli P; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Fedele G; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Source: Frontiers in immunology [Front Immunol] 2026 May 25; Vol. 17, pp. 1816573. Date of Electronic Publication: 2026 May 25 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Serum cytokine profiling reveals CXCL10 (IP-10) as a major predictor of severe COVID-19 outcomes in hospitalized patients during the first pandemic wave in Italy.
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  Data: <searchLink fieldCode="AU" term="%22Muglia+A%22">Muglia A</searchLink>; National PhD Programme in One Health approaches to infectious diseases and life science research, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Petrone+D%22">Petrone D</searchLink>; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Schiavoni+I%22">Schiavoni I</searchLink>; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Santinelli+L%22">Santinelli L</searchLink>; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Leone+P%22">Leone P</searchLink>; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bella+A%22">Bella A</searchLink>; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22d'Ettorre+G%22">d'Ettorre G</searchLink>; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Alessandri+F%22">Alessandri F</searchLink>; Department of Anaesthesia and Intensive Care, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Palamara+AT%22">Palamara AT</searchLink>; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mastroianni+CM%22">Mastroianni CM</searchLink>; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Stefanelli+P%22">Stefanelli P</searchLink>; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Fedele+G%22">Fedele G</searchLink>; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 May 25; Vol. 17, pp. 1816573. <i>Date of Electronic Publication: </i>2026 May 25 (<i>Print Publication: </i>2026).
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