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Genotype Predicts Heart Failure Independent of LVEF, Peak VO2, and NT-proBNP Levels in Hypertrophic Cardiomyopathy.

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Title: Genotype Predicts Heart Failure Independent of LVEF, Peak VO2, and NT-proBNP Levels in Hypertrophic Cardiomyopathy.
Authors: Bakalakos A; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom. Electronic address: a.bakalakos@ucl.ac.uk., Protonotarios A; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom., Pavlou M; Department of Statistical Science, University College London, London, United Kingdom., Cannie DE; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom; Centre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital For Children NHS Foundation Trust, London, United Kingdom., Lorca R; Área del Corazón y Departamento de Genética Molecular, Hospital Universitario Central Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain., Coats CJ; Institute of Cardiovascular Science, University College London, London, United Kingdom; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom., Monda E; Institute of Cardiovascular Science, University College London, London, United Kingdom; Department of Translational Medical Sciences, Inherited and Rare Cardiovascular Diseases, University of Campania 'Luigi Vanvitelli,' Naples, Italy., Savvatis K; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom., Lopes LR; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom., O'Mahony C; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom., Kaski JP; Institute of Cardiovascular Science, University College London, London, United Kingdom; Centre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital For Children NHS Foundation Trust, London, United Kingdom., Lorenzini M; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom., Syrris P; Institute of Cardiovascular Science, University College London, London, United Kingdom., Elliott PM; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.
Source: JACC. Heart failure [JACC Heart Fail] 2026 Jun 08, pp. 103149. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101598241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-1787 (Electronic) Linking ISSN: 22131779 NLM ISO Abbreviation: JACC Heart Fail Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Bakalakos+A%22">Bakalakos A</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom. Electronic address: a.bakalakos@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Protonotarios+A%22">Protonotarios A</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pavlou+M%22">Pavlou M</searchLink>; Department of Statistical Science, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cannie+DE%22">Cannie DE</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom; Centre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital For Children NHS Foundation Trust, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lorca+R%22">Lorca R</searchLink>; Área del Corazón y Departamento de Genética Molecular, Hospital Universitario Central Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.<br /><searchLink fieldCode="AU" term="%22Coats+CJ%22">Coats CJ</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Monda+E%22">Monda E</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Department of Translational Medical Sciences, Inherited and Rare Cardiovascular Diseases, University of Campania 'Luigi Vanvitelli,' Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Savvatis+K%22">Savvatis K</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lopes+LR%22">Lopes LR</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22O'Mahony+C%22">O'Mahony C</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kaski+JP%22">Kaski JP</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Centre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital For Children NHS Foundation Trust, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lorenzini+M%22">Lorenzini M</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Syrris+P%22">Syrris P</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Elliott+PM%22">Elliott PM</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.
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