Long term evaluation of the safety and efficacy of local cooling anesthesia during intravitreal injections: The COOL-2 Trial.

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Bibliographic Details
Title: Long term evaluation of the safety and efficacy of local cooling anesthesia during intravitreal injections: The COOL-2 Trial.
Authors: Khanani AM; Sierra Eye Associates and University of Nevada, Reno School of Medicine, Reno, Nevada, United States of America., Patel SN; The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America., Wykoff CC; Retina Consultants of Texas, Retina Consultants of America, Blanton Eye Institute, Houston Methodist Hospital & Weill Cornell Medical College, Houston, Texas, United States of America., Kim GH; RecensMedical, Ulsan, Korea.; Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Korea., Kuriyan AE; The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.
Source: PloS one [PLoS One] 2026 Jun 10; Vol. 21 (6), pp. e0349554. Date of Electronic Publication: 2026 Jun 10 (Print Publication: 2026).
Publication Type: Journal Article; Multicenter Study; Clinical Trial
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0349554