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Long term evaluation of the safety and efficacy of local cooling anesthesia during intravitreal injections: The COOL-2 Trial.

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Title: Long term evaluation of the safety and efficacy of local cooling anesthesia during intravitreal injections: The COOL-2 Trial.
Authors: Khanani AM; Sierra Eye Associates and University of Nevada, Reno School of Medicine, Reno, Nevada, United States of America., Patel SN; The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America., Wykoff CC; Retina Consultants of Texas, Retina Consultants of America, Blanton Eye Institute, Houston Methodist Hospital & Weill Cornell Medical College, Houston, Texas, United States of America., Kim GH; RecensMedical, Ulsan, Korea.; Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Korea., Kuriyan AE; The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.
Source: PloS one [PLoS One] 2026 Jun 10; Vol. 21 (6), pp. e0349554. Date of Electronic Publication: 2026 Jun 10 (Print Publication: 2026).
Publication Type: Journal Article; Multicenter Study; Clinical Trial
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Khanani+AM%22">Khanani AM</searchLink>; Sierra Eye Associates and University of Nevada, Reno School of Medicine, Reno, Nevada, United States of America.<br /><searchLink fieldCode="AU" term="%22Patel+SN%22">Patel SN</searchLink>; The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Wykoff+CC%22">Wykoff CC</searchLink>; Retina Consultants of Texas, Retina Consultants of America, Blanton Eye Institute, Houston Methodist Hospital & Weill Cornell Medical College, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Kim+GH%22">Kim GH</searchLink>; RecensMedical, Ulsan, Korea.; Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Korea.<br /><searchLink fieldCode="AU" term="%22Kuriyan+AE%22">Kuriyan AE</searchLink>; The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Jun 10; Vol. 21 (6), pp. e0349554. <i>Date of Electronic Publication: </i>2026 Jun 10 (<i>Print Publication: </i>2026).
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