Understanding Transformer-Based Classifications of Medical Text Using a Large Language Model for the Attribution of Feature Importance: Proof-of-Concept Algorithm Development and Validation Study.

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Bibliographic Details
Title: Understanding Transformer-Based Classifications of Medical Text Using a Large Language Model for the Attribution of Feature Importance: Proof-of-Concept Algorithm Development and Validation Study.
Authors: Zhou F; Health Information Research Unit, Department of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada, 1 905-525-9140 ext 22208., Saha A; Department of Oncology, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada., Afzal M; Department of Computer Science, Birmingham City University, Birmingham, United Kingdom., Parrish R; Health Information Research Unit, Department of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada, 1 905-525-9140 ext 22208., Haynes RB; Health Information Research Unit, Department of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada, 1 905-525-9140 ext 22208., Iorio A; Health Information Research Unit, Department of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada, 1 905-525-9140 ext 22208.; Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada., Lokker C; Health Information Research Unit, Department of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada, 1 905-525-9140 ext 22208.
Source: JMIR medical informatics [JMIR Med Inform] 2026 Jun 10; Vol. 14, pp. e81644. Date of Electronic Publication: 2026 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101645109 Publication Model: Electronic Cited Medium: Internet ISSN: 2291-9694 (Electronic) Linking ISSN: 22919694 NLM ISO Abbreviation: JMIR Med Inform Subsets: MEDLINE
Database: MEDLINE Ultimate
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