Solvent-free engineering of a co-amorphous efavirenz-ritonavir system by hot-melt extrusion: Solid-state stabilisation and improved bioavailability.
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| Title: | Solvent-free engineering of a co-amorphous efavirenz-ritonavir system by hot-melt extrusion: Solid-state stabilisation and improved bioavailability. |
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| Authors: | Ghatole S; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, West Bengal 700054, India., Taladhi K; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, West Bengal 700054, India., Kumari M; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, West Bengal 700054, India., Pulimamidi SS; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam 781101, India., Borkar RM; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam 781101, India. Electronic address: roshan.borkar@niperguwahati.ac.in., Roy S; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Kolkata, West Bengal 700054, India., Kaity S; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, West Bengal 700054, India. Electronic address: skaity13@gmail.com. |
| Source: | International journal of pharmaceutics [Int J Pharm] 2026 Jul 10; Vol. 700, pp. 127068. Date of Electronic Publication: 2026 Jun 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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