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Time-resolved immune dynamics in rheumatoid arthritis under methotrexate therapy.

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Title: Time-resolved immune dynamics in rheumatoid arthritis under methotrexate therapy.
Authors: Preglej T; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria., Tosevska A; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria., Brinkmann M; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria., Schatzlmaier P; Center for Pathophysiology, Infectiology and Immunology, Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria; Department of Biological Sciences and Pathobiology, Physiology & Pathophysiology, University of Veterinary Medicine Vienna, Vienna, Austria., Schmidt F; Division of Clinical and Experimental Immunology, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria., Korzhenevich J; Division of Clinical and Experimental Immunology, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria., Simader E; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria., Sieghart D; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria., Hofer P; Department of Pathology, Medical University of Vienna, Vienna, Austria., Krausgruber T; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Center for Medical Data Science, Institute of Artificial Intelligence, Medical University of Vienna, Vienna, Austria., Dobnikar L; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Center for Medical Data Science, Institute of Artificial Intelligence, Medical University of Vienna, Vienna, Austria., Karonitsch T; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria., Kain R; Department of Pathology, Medical University of Vienna, Vienna, Austria., Stockinger H; Center for Pathophysiology, Infectiology and Immunology, Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria., Smolen JS; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria., Ellmeier W; Division of Immunobiology, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria., Padyukov L; Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Rizzi M; Division of Clinical and Experimental Immunology, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria; Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany., Aletaha D; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria., Göschl L; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria. Electronic address: lisa.goeschl@meduniwien.ac.at., Bonelli M; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria. Electronic address: michael.bonelli@meduniwien.ac.at.
Source: Annals of the rheumatic diseases [Ann Rheum Dis] 2026 Jun 10. Date of Electronic Publication: 2026 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Country of Publication: United States NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060 (Electronic) Linking ISSN: 00034967 NLM ISO Abbreviation: Ann Rheum Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Time-resolved immune dynamics in rheumatoid arthritis under methotrexate therapy.
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  Data: <searchLink fieldCode="AU" term="%22Preglej+T%22">Preglej T</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Tosevska+A%22">Tosevska A</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Brinkmann+M%22">Brinkmann M</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Schatzlmaier+P%22">Schatzlmaier P</searchLink>; Center for Pathophysiology, Infectiology and Immunology, Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria; Department of Biological Sciences and Pathobiology, Physiology & Pathophysiology, University of Veterinary Medicine Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Schmidt+F%22">Schmidt F</searchLink>; Division of Clinical and Experimental Immunology, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Korzhenevich+J%22">Korzhenevich J</searchLink>; Division of Clinical and Experimental Immunology, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Simader+E%22">Simader E</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Sieghart+D%22">Sieghart D</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hofer+P%22">Hofer P</searchLink>; Department of Pathology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Krausgruber+T%22">Krausgruber T</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Center for Medical Data Science, Institute of Artificial Intelligence, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Dobnikar+L%22">Dobnikar L</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Bock+C%22">Bock C</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Center for Medical Data Science, Institute of Artificial Intelligence, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Karonitsch+T%22">Karonitsch T</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Kain+R%22">Kain R</searchLink>; Department of Pathology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Stockinger+H%22">Stockinger H</searchLink>; Center for Pathophysiology, Infectiology and Immunology, Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Smolen+JS%22">Smolen JS</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ellmeier+W%22">Ellmeier W</searchLink>; Division of Immunobiology, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Padyukov+L%22">Padyukov L</searchLink>; Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Rizzi+M%22">Rizzi M</searchLink>; Division of Clinical and Experimental Immunology, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria; Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Aletaha+D%22">Aletaha D</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Göschl+L%22">Göschl L</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria. Electronic address: lisa.goeschl@meduniwien.ac.at.<br /><searchLink fieldCode="AU" term="%22Bonelli+M%22">Bonelli M</searchLink>; Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria. Electronic address: michael.bonelli@meduniwien.ac.at.
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        Value: 10.1016/j.ard.2026.05.018
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              Text: 2026 Jun 10
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