Loss of systemic anti-viral immunity and LMP1-driven suppressive myeloid tumour niches converge to shape the immunobiology of Epstein-Barr virus-positive diffuse large B-cell lymphoma.
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| Title: | Loss of systemic anti-viral immunity and LMP1-driven suppressive myeloid tumour niches converge to shape the immunobiology of Epstein-Barr virus-positive diffuse large B-cell lymphoma. |
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| Authors: | Fennell É; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland. eanna.fennell@ul.ie.; Department of Pathology, School of Medicine, University College Cork, Cork, Ireland. eanna.fennell@ul.ie., Law SC; Blood Cancer Research Group, Mater Research, University of Queensland, Translational Research Institute, Brisbane, QLD, Australia., Dowell AC; School of Infection, Inflammation and Immunology, University of Birmingham, Birmingham, UK., Pugh MR; School of Infection, Inflammation and Immunology, University of Birmingham, Birmingham, UK., Enright CM; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland., Ross AM; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland., Hennessy AS; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland., Leahy CI; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland., Nikulina N; Institute for Lung Health (ILH), Justus Liebig University Giessen, Germany and Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Richter AG; Cancer Sciences, University of Birmingham, Birmingham, UK., Mundo L; Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy., Leoncini L; Section of Pathology, Department of Medical Biotechnologies, University of Siena, Siena, Italy., Lazzi S; Section of Pathology, Department of Medical Biotechnologies, University of Siena, Siena, Italy., Siciliano MC; Section of Pathology, Department of Medical Biotechnologies, University of Siena, Siena, Italy., Dojcinov SD; Department of Pathology, Swansea Bay University Health Board, Swansea, UK., Quintanilla-Martinez L; Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany., Young KH; Department of Pathology, Duke University Medical Center and Duke Cancer Institute, Durham, NC, USA., Gandhi MK; Blood Cancer Research Group, Mater Research, University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.; Princess Alexandra Hospital, Brisbane, QLD, Australia., Taylor GS; School of Infection, Inflammation and Immunology, University of Birmingham, Birmingham, UK., Murray PG; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland. pamurray@rcsi-mub.com.; Department of Pathology, School of Medicine, Royal College of Surgeons Ireland, Muharraq, Bahrain. pamurray@rcsi-mub.com. |
| Source: | Leukemia [Leukemia] 2026 Jun 10. Date of Electronic Publication: 2026 Jun 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42271039 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Loss of systemic anti-viral immunity and LMP1-driven suppressive myeloid tumour niches converge to shape the immunobiology of Epstein-Barr virus-positive diffuse large B-cell lymphoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Fennell+É%22">Fennell É</searchLink>; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland. eanna.fennell@ul.ie.; Department of Pathology, School of Medicine, University College Cork, Cork, Ireland. eanna.fennell@ul.ie.<br /><searchLink fieldCode="AU" term="%22Law+SC%22">Law SC</searchLink>; Blood Cancer Research Group, Mater Research, University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Dowell+AC%22">Dowell AC</searchLink>; School of Infection, Inflammation and Immunology, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Pugh+MR%22">Pugh MR</searchLink>; School of Infection, Inflammation and Immunology, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Enright+CM%22">Enright CM</searchLink>; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland.<br /><searchLink fieldCode="AU" term="%22Ross+AM%22">Ross AM</searchLink>; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland.<br /><searchLink fieldCode="AU" term="%22Hennessy+AS%22">Hennessy AS</searchLink>; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland.<br /><searchLink fieldCode="AU" term="%22Leahy+CI%22">Leahy CI</searchLink>; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland.<br /><searchLink fieldCode="AU" term="%22Nikulina+N%22">Nikulina N</searchLink>; Institute for Lung Health (ILH), Justus Liebig University Giessen, Germany and Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.<br /><searchLink fieldCode="AU" term="%22Richter+AG%22">Richter AG</searchLink>; Cancer Sciences, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Mundo+L%22">Mundo L</searchLink>; Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Leoncini+L%22">Leoncini L</searchLink>; Section of Pathology, Department of Medical Biotechnologies, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Lazzi+S%22">Lazzi S</searchLink>; Section of Pathology, Department of Medical Biotechnologies, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Siciliano+MC%22">Siciliano MC</searchLink>; Section of Pathology, Department of Medical Biotechnologies, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Dojcinov+SD%22">Dojcinov SD</searchLink>; Department of Pathology, Swansea Bay University Health Board, Swansea, UK.<br /><searchLink fieldCode="AU" term="%22Quintanilla-Martinez+L%22">Quintanilla-Martinez L</searchLink>; Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Young+KH%22">Young KH</searchLink>; Department of Pathology, Duke University Medical Center and Duke Cancer Institute, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Gandhi+MK%22">Gandhi MK</searchLink>; Blood Cancer Research Group, Mater Research, University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.; Princess Alexandra Hospital, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Taylor+GS%22">Taylor GS</searchLink>; School of Infection, Inflammation and Immunology, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Murray+PG%22">Murray PG</searchLink>; School of Medicine, Bernal Institute, Limerick Digital Cancer Research Centre and Health Research Institute, University of Limerick, Limerick, Ireland. pamurray@rcsi-mub.com.; Department of Pathology, School of Medicine, Royal College of Surgeons Ireland, Muharraq, Bahrain. pamurray@rcsi-mub.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2026 Jun 10. <i>Date of Electronic Publication: </i>2026 Jun 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%2C+Specialist+Journals%22">Nature Publishing Group, Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8704895 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208876924%22">08876924 </searchLink><i>NLM ISO Abbreviation: </i>Leukemia <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42271039 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41375-026-02994-3 Languages: – Code: eng Text: English Titles: – TitleFull: Loss of systemic anti-viral immunity and LMP1-driven suppressive myeloid tumour niches converge to shape the immunobiology of Epstein-Barr virus-positive diffuse large B-cell lymphoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fennell É – PersonEntity: Name: NameFull: Law SC – PersonEntity: Name: NameFull: Dowell AC – PersonEntity: Name: NameFull: Pugh MR – PersonEntity: Name: NameFull: Enright CM – PersonEntity: Name: NameFull: Ross AM – PersonEntity: Name: NameFull: Hennessy AS – PersonEntity: Name: NameFull: Leahy CI – PersonEntity: Name: NameFull: Nikulina N – PersonEntity: Name: NameFull: Richter AG – PersonEntity: Name: NameFull: Mundo L – PersonEntity: Name: NameFull: Leoncini L – PersonEntity: Name: NameFull: Lazzi S – PersonEntity: Name: NameFull: Siciliano MC – PersonEntity: Name: NameFull: Dojcinov SD – PersonEntity: Name: NameFull: Quintanilla-Martinez L – PersonEntity: Name: NameFull: Young KH – PersonEntity: Name: NameFull: Gandhi MK – PersonEntity: Name: NameFull: Taylor GS – PersonEntity: Name: NameFull: Murray PG IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 06 Text: 2026 Jun 10 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1476-5551 Titles: – TitleFull: Leukemia Type: main |
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