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Prioritising and ranking methodological uncertainties in the design, conduct, and analysis of trials aiming to improve health outcomes for those living with multiple long-term conditions: A protocol for a modified Delphi study.

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Title: Prioritising and ranking methodological uncertainties in the design, conduct, and analysis of trials aiming to improve health outcomes for those living with multiple long-term conditions: A protocol for a modified Delphi study.
Authors: Ahmadi A; Division of Public Health and Epidemiology, University of Leicester, Leicester, UK., Zhang L; Division of Public Health and Epidemiology, University of Leicester, Leicester, UK., Bryant N; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Darko N; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Khunti K; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; NIHR Applied Research Collaboration East Midlands, University of Leicester, Leicester, UK.; Leicester British Heart Foundation Centre of Research Excellence, University of Leicester, Leicester, UK.; Diabetes Research Centre, University of Leicester, Leicester, UK., Singh SJ; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Simpson SA; Public Health, School of Health and Well Being, University of Glasgow, Glasgow, UK., Smith SM; Discipline of Public Health and Primary Care, Trinity College, Dublin, Ireland., Taylor RS; Robertson Centre for Biostatistics, School of Health and Well Being, University of Glasgow, Glasgow, UK., Witham MD; AGE Research Group, Translational and Clinical R esearch Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Faculty of Medical Sciences Newcastle University, Newcastle upon Tyne, UK., Hannah Young; Diabetes Research Centre, University of Leicester, Leicester, UK., Gray LJ; Division of Public Health and Epidemiology, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; NIHR Applied Research Collaboration East Midlands, University of Leicester, Leicester, UK.; Leicester British Heart Foundation Centre of Research Excellence, University of Leicester, Leicester, UK.
Source: Journal of multimorbidity and comorbidity [J Multimorb Comorb] 2026 Jun 08; Vol. 16, pp. 26335565261459136. Date of Electronic Publication: 2026 Jun 08 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Ltd Country of Publication: England NLM ID: 9918333280706676 Publication Model: eCollection Cited Medium: Internet ISSN: 2633-5565 (Electronic) Linking ISSN: 26335565 NLM ISO Abbreviation: J Multimorb Comorb Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Ahmadi+A%22">Ahmadi A</searchLink>; Division of Public Health and Epidemiology, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Division of Public Health and Epidemiology, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Bryant+N%22">Bryant N</searchLink>; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Darko+N%22">Darko N</searchLink>; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Khunti+K%22">Khunti K</searchLink>; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; NIHR Applied Research Collaboration East Midlands, University of Leicester, Leicester, UK.; Leicester British Heart Foundation Centre of Research Excellence, University of Leicester, Leicester, UK.; Diabetes Research Centre, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Singh+SJ%22">Singh SJ</searchLink>; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Simpson+SA%22">Simpson SA</searchLink>; Public Health, School of Health and Well Being, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Smith+SM%22">Smith SM</searchLink>; Discipline of Public Health and Primary Care, Trinity College, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Taylor+RS%22">Taylor RS</searchLink>; Robertson Centre for Biostatistics, School of Health and Well Being, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Witham+MD%22">Witham MD</searchLink>; AGE Research Group, Translational and Clinical R esearch Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Faculty of Medical Sciences Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Hannah+Young%22">Hannah Young</searchLink>; Diabetes Research Centre, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Gray+LJ%22">Gray LJ</searchLink>; Division of Public Health and Epidemiology, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; NIHR Applied Research Collaboration East Midlands, University of Leicester, Leicester, UK.; Leicester British Heart Foundation Centre of Research Excellence, University of Leicester, Leicester, UK.
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              Text: 2026 Jun 08
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