Charting human cellular senescence in aging and disease.

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Title: Charting human cellular senescence in aging and disease.
Authors: Suryadevara V; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: vidyani@stanford.edu., Farzad N; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT, USA., Yang M; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT, USA., Xu K; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY, USA., Tsankov A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY, USA., Thompson RC; Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY 10029, USA., Sloan N; Department of Neurology, Columbia Irving Medical Center, New York, NY, USA; New York Genome Center, New York, NY, USA., Phatnani H; Department of Neurology, Columbia Irving Medical Center, New York, NY, USA; New York Genome Center, New York, NY, USA., Olinger B; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA., Mares JA; Department of Neurology, Columbia Irving Medical Center, New York, NY, USA., Lund AN; Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY 10029, USA., Li D; Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY, USA., Gorospe M; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD, USA., Ding L; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63108, USA., Beckmann N; Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY 10029, USA., Basisty N; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA., Anerillas C; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63108, USA; Tissue and Organ Homeostasis Program, Centro de Biología Molecular Severo Ochoa (CBM), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain; Instituto Aragones de Ciencias de la Salud (IACS) and Fundación Agencia Aragonesa para la Investigación y el Desarrollo (ARAID), Zaragoza, Spain., Robbins P; Department of Biochemistry, Molecular Biology and Biophysics, Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA., Fan R; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT, USA. Electronic address: rong.fan@yale.edu.
Corporate Authors: NIH SenNet consortium
Source: Cell [Cell] 2026 Jun 11; Vol. 189 (12), pp. 3501-3505.
Publication Type: Journal Article; Review
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Charting human cellular senescence in aging and disease.
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  Data: <searchLink fieldCode="AU" term="%22Suryadevara+V%22">Suryadevara V</searchLink>; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: vidyani@stanford.edu.<br /><searchLink fieldCode="AU" term="%22Farzad+N%22">Farzad N</searchLink>; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Yang+M%22">Yang M</searchLink>; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Xu+K%22">Xu K</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tsankov+A%22">Tsankov A</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+RC%22">Thompson RC</searchLink>; Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Sloan+N%22">Sloan N</searchLink>; Department of Neurology, Columbia Irving Medical Center, New York, NY, USA; New York Genome Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Phatnani+H%22">Phatnani H</searchLink>; Department of Neurology, Columbia Irving Medical Center, New York, NY, USA; New York Genome Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Olinger+B%22">Olinger B</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Mares+JA%22">Mares JA</searchLink>; Department of Neurology, Columbia Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lund+AN%22">Lund AN</searchLink>; Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gorospe+M%22">Gorospe M</searchLink>; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ding+L%22">Ding L</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63108, USA.<br /><searchLink fieldCode="AU" term="%22Beckmann+N%22">Beckmann N</searchLink>; Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Basisty+N%22">Basisty N</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Anerillas+C%22">Anerillas C</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63108, USA; Tissue and Organ Homeostasis Program, Centro de Biología Molecular Severo Ochoa (CBM), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain; Instituto Aragones de Ciencias de la Salud (IACS) and Fundación Agencia Aragonesa para la Investigación y el Desarrollo (ARAID), Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Robbins+P%22">Robbins P</searchLink>; Department of Biochemistry, Molecular Biology and Biophysics, Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Fan+R%22">Fan R</searchLink>; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT, USA. Electronic address: rong.fan@yale.edu.
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  Data: <searchLink fieldCode="CA" term="%22NIH+SenNet+consortium%22">NIH SenNet consortium</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2026 Jun 11; Vol. 189 (12), pp. 3501-3505.
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              Text: 2026 Jun 11
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