Clinical predictors of response to Atezolizumab-bevacizumab in Child-Pugh B patients with hepatocellular carcinoma.
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| Title: | Clinical predictors of response to Atezolizumab-bevacizumab in Child-Pugh B patients with hepatocellular carcinoma. |
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| Authors: | Odent AV; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Service d'Hépatologie, AP-HP Avicenne, France., Campani C; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Department of Experimental and Clinical Medicine, Internal Medicine and Hepatology Unit, University of Firenze, Florence, Italy., Bouattour M; AP-HP, Liver Cancer and Innovative Therapy Unit, Hôpital Beaujon, 100 Boulevard du Général Leclerc, 92110, Clichy, France; Centre de Recherche Sur L'Inflammation (CRI), INSERM, U1149, CNRS, ERL 8252, F-75018, Paris, France., Touchefeu Y; Nantes Université, CHU Nantes, Institut des Maladies de l'Appareil Digestif (IMAD), Hépato-Gastroentérologie, Inserm CIC 1413, F-44000 Nantes, France., Delhoume V; Nantes Université, CHU Nantes, Institut des Maladies de l'Appareil Digestif (IMAD), Hépato-Gastroentérologie, Inserm CIC 1413, F-44000 Nantes, France., Rosmorduc O; Centre Hépato-Biliaire, Paul-Brousse Hospital, Assistance Publique-Hôpitaux de Paris, Villejuif, France., Pascale A; Centre Hépato-Biliaire, Paul-Brousse Hospital, Assistance Publique-Hôpitaux de Paris, Villejuif, France; Faculté de Médecine, Sorbonne Université and Paris Saclay Université, Le Kremlin-Bicêtre, France; Unité Mixte de Recherche 1193, Paris-Saclay University, INSERM, Villejuif, France., An J; Gastroenterology and Hepatology, Hanyang University College of Medicine, Guri, Korea., Lee HC; Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Asan Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Regnault H; Service d'Hépatologie, AP-HP Henri Mondor, Créteil, France., Thabut D; Hepatogastroenterology Department, La Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Paris, France; INSERM UMR_S 938, Centre de recherche Saint-Antoine, Maladies métaboliques, biliaires et fibro-inflammatoire du foie, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France., Amaddeo G; Service d'Hépatologie, AP-HP Henri Mondor, Créteil, France., Ningararhi M; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; CHU Lille, Maladies de l'Appareil Digestif, Université de Lille, Lille, France., Olivier-Hourmand I; Service d'hépato-gastroentérologie, CHU de Caen, ERN RARE-LIVER, France., Metivier C; Service d'hépato-gastroentérologie, CHU de Caen, ERN RARE-LIVER, France., Ronot M; Department of Radiology, Hôpital Beaujon, AP-HP.Nord, 100 Boulevard du Général Leclerc, 92110 Clichy., Ntandja-Wandji L; CHU Lille, Maladies de l'Appareil Digestif, Université de Lille, Lille, France., Ozenne V; Service d'Hépatologie, AP-HP Saint-Antoine, France., Sidali S; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; AP-HP, Liver Cancer and Innovative Therapy Unit, Hôpital Beaujon, 100 Boulevard du Général Leclerc, 92110, Clichy, France., Marra F; Service d'Hépatologie, AP-HP Avicenne, France., Hollande C; AP-HP, Liver Cancer and Innovative Therapy Unit, Hôpital Beaujon, 100 Boulevard du Général Leclerc, 92110, Clichy, France., Ganne-Carrié N; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Service d'Hépatologie, AP-HP Avicenne, France; Unité de Formation et de Recherche Santé Médecine et Biologie Humaine, Université Paris 13, Communauté d'Universités et Etablissements Sorbonne Paris Cité, Paris, France., Nahon P; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Service d'Hépatologie, AP-HP Avicenne, France; Unité de Formation et de Recherche Santé Médecine et Biologie Humaine, Université Paris 13, Communauté d'Universités et Etablissements Sorbonne Paris Cité, Paris, France., Peron JM; Service D'hépatologie, Hôpital Rangueil, CHU Toulouse, Toulouse, France., Lequoy M; INSERM UMR_S 938, Centre de recherche Saint-Antoine, Maladies métaboliques, biliaires et fibro-inflammatoire du foie, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France; Service d'Hépatologie, AP-HP Saint-Antoine, France., Sharma R; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK., Trepo E; Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, Hôpital Universitaire de Bruxelles, B-1070, Brussels, Belgium., Mouri S; Hepatogastroenterology Department, La Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Paris, France., Allaire M; Hepatogastroenterology Department, La Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Paris, France; INSERM UMR 1138, Centre de recherche des Cordeliers, « Genomic instability, metabolism, immunity and liver tumorigenesis », 75006 Paris, France., Shim JH; Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Asan Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Nault JC; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Service d'Hépatologie, AP-HP Avicenne, France; Unité de Formation et de Recherche Santé Médecine et Biologie Humaine, Université Paris 13, Communauté d'Universités et Etablissements Sorbonne Paris Cité, Paris, France. Electronic address: naultjc@gmail.com. |
| Corporate Authors: | Paris Liver Cancer Group |
| Source: | JHEP reports : innovation in hepatology [JHEP Rep] 2026 Jun 11, pp. 101915. Date of Electronic Publication: 2026 Jun 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42276190 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Clinical predictors of response to Atezolizumab-bevacizumab in Child-Pugh B patients with hepatocellular carcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Odent+AV%22">Odent AV</searchLink>; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Service d'Hépatologie, AP-HP Avicenne, France.<br /><searchLink fieldCode="AU" term="%22Campani+C%22">Campani C</searchLink>; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Department of Experimental and Clinical Medicine, Internal Medicine and Hepatology Unit, University of Firenze, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Bouattour+M%22">Bouattour M</searchLink>; AP-HP, Liver Cancer and Innovative Therapy Unit, Hôpital Beaujon, 100 Boulevard du Général Leclerc, 92110, Clichy, France; Centre de Recherche Sur L'Inflammation (CRI), INSERM, U1149, CNRS, ERL 8252, F-75018, Paris, France.<br /><searchLink fieldCode="AU" term="%22Touchefeu+Y%22">Touchefeu Y</searchLink>; Nantes Université, CHU Nantes, Institut des Maladies de l'Appareil Digestif (IMAD), Hépato-Gastroentérologie, Inserm CIC 1413, F-44000 Nantes, France.<br /><searchLink fieldCode="AU" term="%22Delhoume+V%22">Delhoume V</searchLink>; Nantes Université, CHU Nantes, Institut des Maladies de l'Appareil Digestif (IMAD), Hépato-Gastroentérologie, Inserm CIC 1413, F-44000 Nantes, France.<br /><searchLink fieldCode="AU" term="%22Rosmorduc+O%22">Rosmorduc O</searchLink>; Centre Hépato-Biliaire, Paul-Brousse Hospital, Assistance Publique-Hôpitaux de Paris, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Pascale+A%22">Pascale A</searchLink>; Centre Hépato-Biliaire, Paul-Brousse Hospital, Assistance Publique-Hôpitaux de Paris, Villejuif, France; Faculté de Médecine, Sorbonne Université and Paris Saclay Université, Le Kremlin-Bicêtre, France; Unité Mixte de Recherche 1193, Paris-Saclay University, INSERM, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22An+J%22">An J</searchLink>; Gastroenterology and Hepatology, Hanyang University College of Medicine, Guri, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HC%22">Lee HC</searchLink>; Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Asan Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Regnault+H%22">Regnault H</searchLink>; Service d'Hépatologie, AP-HP Henri Mondor, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Thabut+D%22">Thabut D</searchLink>; Hepatogastroenterology Department, La Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Paris, France; INSERM UMR&#95;S 938, Centre de recherche Saint-Antoine, Maladies métaboliques, biliaires et fibro-inflammatoire du foie, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France.<br /><searchLink fieldCode="AU" term="%22Amaddeo+G%22">Amaddeo G</searchLink>; Service d'Hépatologie, AP-HP Henri Mondor, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Ningararhi+M%22">Ningararhi M</searchLink>; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; CHU Lille, Maladies de l'Appareil Digestif, Université de Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Olivier-Hourmand+I%22">Olivier-Hourmand I</searchLink>; Service d'hépato-gastroentérologie, CHU de Caen, ERN RARE-LIVER, France.<br /><searchLink fieldCode="AU" term="%22Metivier+C%22">Metivier C</searchLink>; Service d'hépato-gastroentérologie, CHU de Caen, ERN RARE-LIVER, France.<br /><searchLink fieldCode="AU" term="%22Ronot+M%22">Ronot M</searchLink>; Department of Radiology, Hôpital Beaujon, AP-HP.Nord, 100 Boulevard du Général Leclerc, 92110 Clichy.<br /><searchLink fieldCode="AU" term="%22Ntandja-Wandji+L%22">Ntandja-Wandji L</searchLink>; CHU Lille, Maladies de l'Appareil Digestif, Université de Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Ozenne+V%22">Ozenne V</searchLink>; Service d'Hépatologie, AP-HP Saint-Antoine, France.<br /><searchLink fieldCode="AU" term="%22Sidali+S%22">Sidali S</searchLink>; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; AP-HP, Liver Cancer and Innovative Therapy Unit, Hôpital Beaujon, 100 Boulevard du Général Leclerc, 92110, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Marra+F%22">Marra F</searchLink>; Service d'Hépatologie, AP-HP Avicenne, France.<br /><searchLink fieldCode="AU" term="%22Hollande+C%22">Hollande C</searchLink>; AP-HP, Liver Cancer and Innovative Therapy Unit, Hôpital Beaujon, 100 Boulevard du Général Leclerc, 92110, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Ganne-Carrié+N%22">Ganne-Carrié N</searchLink>; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Service d'Hépatologie, AP-HP Avicenne, France; Unité de Formation et de Recherche Santé Médecine et Biologie Humaine, Université Paris 13, Communauté d'Universités et Etablissements Sorbonne Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Nahon+P%22">Nahon P</searchLink>; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Service d'Hépatologie, AP-HP Avicenne, France; Unité de Formation et de Recherche Santé Médecine et Biologie Humaine, Université Paris 13, Communauté d'Universités et Etablissements Sorbonne Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Peron+JM%22">Peron JM</searchLink>; Service D'hépatologie, Hôpital Rangueil, CHU Toulouse, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Lequoy+M%22">Lequoy M</searchLink>; INSERM UMR&#95;S 938, Centre de recherche Saint-Antoine, Maladies métaboliques, biliaires et fibro-inflammatoire du foie, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France; Service d'Hépatologie, AP-HP Saint-Antoine, France.<br /><searchLink fieldCode="AU" term="%22Sharma+R%22">Sharma R</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK.<br /><searchLink fieldCode="AU" term="%22Trepo+E%22">Trepo E</searchLink>; Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, Hôpital Universitaire de Bruxelles, B-1070, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Mouri+S%22">Mouri S</searchLink>; Hepatogastroenterology Department, La Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Allaire+M%22">Allaire M</searchLink>; Hepatogastroenterology Department, La Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Paris, France; INSERM UMR 1138, Centre de recherche des Cordeliers, « Genomic instability, metabolism, immunity and liver tumorigenesis », 75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Shim+JH%22">Shim JH</searchLink>; Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Asan Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Nault+JC%22">Nault JC</searchLink>; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, team « Functional Genomics of Solid Tumors », F-75006 Paris, France; Service d'Hépatologie, AP-HP Avicenne, France; Unité de Formation et de Recherche Santé Médecine et Biologie Humaine, Université Paris 13, Communauté d'Universités et Etablissements Sorbonne Paris Cité, Paris, France. Electronic address: naultjc@gmail.com. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Paris+Liver+Cancer+Group%22">Paris Liver Cancer Group</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101761237%22">JHEP reports : innovation in hepatology</searchLink> [JHEP Rep] 2026 Jun 11, pp. 101915. <i>Date of Electronic Publication: </i>2026 Jun 11. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101761237 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2589-5559 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225895559%22">25895559 </searchLink><i>NLM ISO Abbreviation: </i>JHEP Rep <i>Subsets: </i>MEDLINE |
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