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GSH-activatable rare-earth nanoprobe for NIR-II fluorescence imaging-guided surgery and enhanced chemotherapy/chemodynamic therapy of breast cancer.

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Title: GSH-activatable rare-earth nanoprobe for NIR-II fluorescence imaging-guided surgery and enhanced chemotherapy/chemodynamic therapy of breast cancer.
Authors: Lin LL; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China; Research Department of Xiamen Hospital of Traditional Chinese Medicine & Xiamen Hospital, Dongzhimen Hospital, Beijing University of Chinese Medicine, Xiamen, 361015, China., Bai JW; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China; Department of Rehabilitation and Palliative Medicine, Yunnan Cancer Hospital & the Third Affiliated Hospital of Kunming Medical University &Peking University Cancer Hospital Yunnan, Kunming, 650118, China., Song L; State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China; Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Xiamen, 361021, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Lou KL; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China., Gao YY; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China., Chen HY; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China., Lin SJ; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China., Li CX; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China., Zhang Y; State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China; Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Xiamen, 361021, China; Department of Rehabilitation and Palliative Medicine, Yunnan Cancer Hospital & the Third Affiliated Hospital of Kunming Medical University &Peking University Cancer Hospital Yunnan, Kunming, 650118, China. Electronic address: zhangy@fjirsm.ac.cn., Zhang GJ; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China. Electronic address: zhangguojun@kmmu.edu.cn.
Source: Cancer letters [Cancer Lett] 2026 Sep 28; Vol. 656, pp. 218677. Date of Electronic Publication: 2026 Jun 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: GSH-activatable rare-earth nanoprobe for NIR-II fluorescence imaging-guided surgery and enhanced chemotherapy/chemodynamic therapy of breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Lin+LL%22">Lin LL</searchLink>; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China; Research Department of Xiamen Hospital of Traditional Chinese Medicine & Xiamen Hospital, Dongzhimen Hospital, Beijing University of Chinese Medicine, Xiamen, 361015, China.<br /><searchLink fieldCode="AU" term="%22Bai+JW%22">Bai JW</searchLink>; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China; Department of Rehabilitation and Palliative Medicine, Yunnan Cancer Hospital & the Third Affiliated Hospital of Kunming Medical University &Peking University Cancer Hospital Yunnan, Kunming, 650118, China.<br /><searchLink fieldCode="AU" term="%22Song+L%22">Song L</searchLink>; State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China; Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Xiamen, 361021, China; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Lou+KL%22">Lou KL</searchLink>; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China.<br /><searchLink fieldCode="AU" term="%22Gao+YY%22">Gao YY</searchLink>; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China.<br /><searchLink fieldCode="AU" term="%22Chen+HY%22">Chen HY</searchLink>; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China.<br /><searchLink fieldCode="AU" term="%22Lin+SJ%22">Lin SJ</searchLink>; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China.<br /><searchLink fieldCode="AU" term="%22Li+CX%22">Li CX</searchLink>; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China; Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Xiamen, 361021, China; Department of Rehabilitation and Palliative Medicine, Yunnan Cancer Hospital & the Third Affiliated Hospital of Kunming Medical University &Peking University Cancer Hospital Yunnan, Kunming, 650118, China. Electronic address: zhangy@fjirsm.ac.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+GJ%22">Zhang GJ</searchLink>; The Breast Center and the Cancer Institute of Yunnan Cancer Hospital, Yunnan Key Laboratory of Molecular Imaging in Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, Yunnan, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer & Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361101, China. Electronic address: zhangguojun@kmmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%227600053%22">Cancer letters</searchLink> [Cancer Lett] 2026 Sep 28; Vol. 656, pp. 218677. <i>Date of Electronic Publication: </i>2026 Jun 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ireland%22">Elsevier Science Ireland </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>7600053 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203043835%22">03043835 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Lett <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.canlet.2026.218677
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        Text: English
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              Text: 2026 Sep 28
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