Long-term polystyrene nanoplastics exposure aggravates retinal inflammation and photoreceptor degeneration through microglial SPP1 signaling and neutrophil extracellular traps formation.

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Title: Long-term polystyrene nanoplastics exposure aggravates retinal inflammation and photoreceptor degeneration through microglial SPP1 signaling and neutrophil extracellular traps formation.
Authors: Zhou W; Department of Ophthalmology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 401336, China. zhoucc@hospital.cqmu.edu.cn., Chen X; Dermatology Center, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.; Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.; Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China., Li J; College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, 311121, China., He J; Department of Ophthalmology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. fffreddd@sjtu.edu.cn.
Source: Journal of translational medicine [J Transl Med] 2026 Jun 11; Vol. 24 (1). Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Long-term polystyrene nanoplastics exposure aggravates retinal inflammation and photoreceptor degeneration through microglial SPP1 signaling and neutrophil extracellular traps formation.
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  Data: <searchLink fieldCode="AU" term="%22Zhou+W%22">Zhou W</searchLink>; Department of Ophthalmology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 401336, China. zhoucc@hospital.cqmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Dermatology Center, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.; Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.; Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, 311121, China.<br /><searchLink fieldCode="AU" term="%22He+J%22">He J</searchLink>; Department of Ophthalmology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. fffreddd@sjtu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Jun 11; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Jun 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1186/s12967-026-08405-6
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      – Code: eng
        Text: English
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      – TitleFull: Long-term polystyrene nanoplastics exposure aggravates retinal inflammation and photoreceptor degeneration through microglial SPP1 signaling and neutrophil extracellular traps formation.
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            NameFull: Chen X
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            NameFull: Li J
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            – D: 11
              M: 06
              Text: 2026 Jun 11
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              Y: 2026
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