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Concordance of Actionable Driver Alterations Between Primary Lung Adenocarcinoma and Paired Thoracic Metastases: A Prospective Next-Generation Sequencing Study.

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Title: Concordance of Actionable Driver Alterations Between Primary Lung Adenocarcinoma and Paired Thoracic Metastases: A Prospective Next-Generation Sequencing Study.
Authors: Bertolaccini L; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Lombardi M; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Chiari M; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Rappa A; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Casiraghi M; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., D'Ercole M; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Mazzella A; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Lo Iacono G; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Mohamed S; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Midolo De Luca V; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Fusco N; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Guerini Rocco E; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy., Spaggiari L; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Source: Cancers [Cancers (Basel)] 2026 May 28; Vol. 18 (11). Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Concordance of Actionable Driver Alterations Between Primary Lung Adenocarcinoma and Paired Thoracic Metastases: A Prospective Next-Generation Sequencing Study.
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  Data: <searchLink fieldCode="AU" term="%22Bertolaccini+L%22">Bertolaccini L</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lombardi+M%22">Lombardi M</searchLink>; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Chiari+M%22">Chiari M</searchLink>; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rappa+A%22">Rappa A</searchLink>; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Casiraghi+M%22">Casiraghi M</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22D'Ercole+M%22">D'Ercole M</searchLink>; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzella+A%22">Mazzella A</searchLink>; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lo+Iacono+G%22">Lo Iacono G</searchLink>; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mohamed+S%22">Mohamed S</searchLink>; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Midolo+De+Luca+V%22">Midolo De Luca V</searchLink>; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fusco+N%22">Fusco N</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Guerini+Rocco+E%22">Guerini Rocco E</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Division of Pathology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Spaggiari+L%22">Spaggiari L</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy.; Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101526829%22">Cancers</searchLink> [Cancers (Basel)] 2026 May 28; Vol. 18 (11). <i>Date of Electronic Publication: </i>2026 May 28.
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        Value: 10.3390/cancers18111773
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              Text: 2026 May 28
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