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Histone succinylation directly inhibits Jumonji domain demethylases and stabilizes repressive chromatin states.

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Title: Histone succinylation directly inhibits Jumonji domain demethylases and stabilizes repressive chromatin states.
Authors: Graff S; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA., Stransky S; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA., Kraz I; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA., Duraivelan K; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA., Poppel A; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA., Chatoff A; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Snyder NW; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Garforth S; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA., Shechter D; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA., Pablo Maianti J; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA., Sidoli S; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jun 01. Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Histone succinylation directly inhibits Jumonji domain demethylases and stabilizes repressive chromatin states.
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  Data: <searchLink fieldCode="AU" term="%22Graff+S%22">Graff S</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Stransky+S%22">Stransky S</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kraz+I%22">Kraz I</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Duraivelan+K%22">Duraivelan K</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Poppel+A%22">Poppel A</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chatoff+A%22">Chatoff A</searchLink>; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Snyder+NW%22">Snyder NW</searchLink>; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Garforth+S%22">Garforth S</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shechter+D%22">Shechter D</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pablo+Maianti+J%22">Pablo Maianti J</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sidoli+S%22">Sidoli S</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, USA.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.64898/2026.05.29.728167
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              Text: 2026 Jun 01
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