Generative design of programmable asymmetric β-barrel nanopores.

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Title: Generative design of programmable asymmetric β-barrel nanopores.
Authors: Philomin A; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Sonigra R; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Majumder S; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA., Lin HM; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA., Li Y; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA 98105, USA., Xue F; ReLER Lab, AAII, University of Technology Sydney, Sydney, NSW, 2007, Australia., Kibler RD; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA., Coventry B; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA., Baldus CK; Maseeh Department of Civil, Architectural, and Environmental Engineering, University of Texas at Austin, TX, USA., Trapido E; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Bioengineering, University of Washington, Seattle, WA 98105, USA., Medeiros A; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Chemical Engineering, University of Washington, Seattle, WA 98105, USA., Bera AK; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA., Kang A; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA., Mendoza J; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA., Kumar M; Maseeh Department of Civil, Architectural, and Environmental Engineering, University of Texas at Austin, TX, USA.; McKetta Department of Chemical Engineering, University of Texas at Austin, TX, USA., Yang Y; ReLER Lab, CCAI, Zhejiang University, Hangzhou, China., Baker D; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jun 04. Date of Electronic Publication: 2026 Jun 04.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Generative design of programmable asymmetric β-barrel nanopores.
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  Data: <searchLink fieldCode="AU" term="%22Philomin+A%22">Philomin A</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Sonigra+R%22">Sonigra R</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Majumder+S%22">Majumder S</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Lin+HM%22">Lin HM</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA 98105, USA.<br /><searchLink fieldCode="AU" term="%22Xue+F%22">Xue F</searchLink>; ReLER Lab, AAII, University of Technology Sydney, Sydney, NSW, 2007, Australia.<br /><searchLink fieldCode="AU" term="%22Kibler+RD%22">Kibler RD</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Coventry+B%22">Coventry B</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Baldus+CK%22">Baldus CK</searchLink>; Maseeh Department of Civil, Architectural, and Environmental Engineering, University of Texas at Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Trapido+E%22">Trapido E</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Bioengineering, University of Washington, Seattle, WA 98105, USA.<br /><searchLink fieldCode="AU" term="%22Medeiros+A%22">Medeiros A</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Department of Chemical Engineering, University of Washington, Seattle, WA 98105, USA.<br /><searchLink fieldCode="AU" term="%22Bera+AK%22">Bera AK</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Kang+A%22">Kang A</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Mendoza+J%22">Mendoza J</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+M%22">Kumar M</searchLink>; Maseeh Department of Civil, Architectural, and Environmental Engineering, University of Texas at Austin, TX, USA.; McKetta Department of Chemical Engineering, University of Texas at Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; ReLER Lab, CCAI, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Baker+D%22">Baker D</searchLink>; Department of Biochemistry, Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA.
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