Rational engineering of facultative anaerobiosis enables commensal survival in the oxygenated gut.

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Title: Rational engineering of facultative anaerobiosis enables commensal survival in the oxygenated gut.
Authors: Rose AE; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN., Langford-Butler M; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN., Spiga L; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN., Bak DW; Department of Chemistry, Boston College, Chestnut Hill, MA., Neal M; Department of Pediatrics, University of California, San Diego, CA., Shen M; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN., Calcutt MW; Mass Spectrometry Research Center, Department of Biochemistry, Vanderbilt University, Nashville, TN., Fansler RT; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN., Rohaun SK; Department of Microbiology, University of Illinois, Urbana, IL., Feron M; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN., Schrimpe-Rutledge AC; Department of Chemistry and Center for Innovative Technology, Vanderbilt University, Nashville, TN., Berdy B; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA., Codreanu SG; Department of Chemistry and Center for Innovative Technology, Vanderbilt University, Nashville, TN., Sherrod SD; Department of Chemistry and Center for Innovative Technology, Vanderbilt University, Nashville, TN., Hale OF; Department of Biological Sciences, Vanderbilt University, Nashville, TN.; Evolutionary Studies Initiative, Vanderbilt University, Nashville, TN., Livny J; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA., McLean JA; Department of Chemistry and Center for Innovative Technology, Vanderbilt University, Nashville, TN., Zengler K; Department of Pediatrics, University of California, San Diego, CA.; Center for Microbiome Innovation, University of California, San Diego, CA.; Program in Materials Science and Engineering, University of California, San Diego, La Jolla, CA., Behringer MG; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.; Department of Biological Sciences, Vanderbilt University, Nashville, TN.; Evolutionary Studies Initiative, Vanderbilt University, Nashville, TN., Weerapana E; Department of Chemistry, Boston College, Chestnut Hill, MA., Imlay JA; Department of Microbiology, University of Illinois, Urbana, IL., Zhu W; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.; Lead Contact.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jun 06. Date of Electronic Publication: 2026 Jun 06.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Rational engineering of facultative anaerobiosis enables commensal survival in the oxygenated gut.
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  Data: <searchLink fieldCode="AU" term="%22Rose+AE%22">Rose AE</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Langford-Butler+M%22">Langford-Butler M</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Spiga+L%22">Spiga L</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Bak+DW%22">Bak DW</searchLink>; Department of Chemistry, Boston College, Chestnut Hill, MA.<br /><searchLink fieldCode="AU" term="%22Neal+M%22">Neal M</searchLink>; Department of Pediatrics, University of California, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Shen+M%22">Shen M</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Calcutt+MW%22">Calcutt MW</searchLink>; Mass Spectrometry Research Center, Department of Biochemistry, Vanderbilt University, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Fansler+RT%22">Fansler RT</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Rohaun+SK%22">Rohaun SK</searchLink>; Department of Microbiology, University of Illinois, Urbana, IL.<br /><searchLink fieldCode="AU" term="%22Feron+M%22">Feron M</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Schrimpe-Rutledge+AC%22">Schrimpe-Rutledge AC</searchLink>; Department of Chemistry and Center for Innovative Technology, Vanderbilt University, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Berdy+B%22">Berdy B</searchLink>; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Codreanu+SG%22">Codreanu SG</searchLink>; Department of Chemistry and Center for Innovative Technology, Vanderbilt University, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Sherrod+SD%22">Sherrod SD</searchLink>; Department of Chemistry and Center for Innovative Technology, Vanderbilt University, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Hale+OF%22">Hale OF</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN.; Evolutionary Studies Initiative, Vanderbilt University, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Livny+J%22">Livny J</searchLink>; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22McLean+JA%22">McLean JA</searchLink>; Department of Chemistry and Center for Innovative Technology, Vanderbilt University, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Zengler+K%22">Zengler K</searchLink>; Department of Pediatrics, University of California, San Diego, CA.; Center for Microbiome Innovation, University of California, San Diego, CA.; Program in Materials Science and Engineering, University of California, San Diego, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Behringer+MG%22">Behringer MG</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.; Department of Biological Sciences, Vanderbilt University, Nashville, TN.; Evolutionary Studies Initiative, Vanderbilt University, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Weerapana+E%22">Weerapana E</searchLink>; Department of Chemistry, Boston College, Chestnut Hill, MA.<br /><searchLink fieldCode="AU" term="%22Imlay+JA%22">Imlay JA</searchLink>; Department of Microbiology, University of Illinois, Urbana, IL.<br /><searchLink fieldCode="AU" term="%22Zhu+W%22">Zhu W</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.; Lead Contact.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Jun 06. <i>Date of Electronic Publication: </i>2026 Jun 06.
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