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The COPI coatomer influences LDL receptor activity, hepatic lipid storage, and apoB secretion.

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Title: The COPI coatomer influences LDL receptor activity, hepatic lipid storage, and apoB secretion.
Authors: Panteloglou G; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Robert J; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Smit M; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands., Huijkman N; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands., Kloosterhuis N; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands., Law CS; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, U.S.A., Woods B; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Othman A; Functional Genomics Center, University of Zurich and ETH Zurich, Zurich, Switzerland., Kleber ME; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.; Synlab MVZ Humangenetik Mannheim, Mannheim, Germany., Delgado GE; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Tarugi P; Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Lone MA; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Wolters JC; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands., Rimbert A; Nantes Université, CNRS, Inserm, l'institut du thorax, F-44000 Nantes, France., Kerksiek A; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany., Lütjohann D; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany., Rohrer L; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Zanoni P; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Kakava S; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Häusler S; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Schlumpf E; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland., Futema M; Cardiovascular and Genomics Research Institute, St George's School of Health and Medical Sciences, City St Georges University of London, London, United Kingdom.; Institute of Cardiovascular Science, University College London, London, United Kingdom., Humphries SE; Institute of Cardiovascular Science, University College London, London, United Kingdom., Chou J; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA., März W; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.; Synlab MVZ Humangenetik Mannheim, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Geha RS; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Shum AK; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, U.S.A., Kuivenhoven JA; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands., van de Sluis B; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands., von Eckardstein A; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jun 03. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Panteloglou+G%22">Panteloglou G</searchLink>; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Robert+J%22">Robert J</searchLink>; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Smit+M%22">Smit M</searchLink>; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Huijkman+N%22">Huijkman N</searchLink>; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kloosterhuis+N%22">Kloosterhuis N</searchLink>; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Law+CS%22">Law CS</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, U.S.A.<br /><searchLink fieldCode="AU" term="%22Woods+B%22">Woods B</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Othman+A%22">Othman A</searchLink>; Functional Genomics Center, University of Zurich and ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kleber+ME%22">Kleber ME</searchLink>; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.; Synlab MVZ Humangenetik Mannheim, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Delgado+GE%22">Delgado GE</searchLink>; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Tarugi+P%22">Tarugi P</searchLink>; Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Lone+MA%22">Lone MA</searchLink>; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wolters+JC%22">Wolters JC</searchLink>; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Rimbert+A%22">Rimbert A</searchLink>; Nantes Université, CNRS, Inserm, l'institut du thorax, F-44000 Nantes, France.<br /><searchLink fieldCode="AU" term="%22Kerksiek+A%22">Kerksiek A</searchLink>; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Lütjohann+D%22">Lütjohann D</searchLink>; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Rohrer+L%22">Rohrer L</searchLink>; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zanoni+P%22">Zanoni P</searchLink>; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kakava+S%22">Kakava S</searchLink>; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Häusler+S%22">Häusler S</searchLink>; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schlumpf+E%22">Schlumpf E</searchLink>; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Futema+M%22">Futema M</searchLink>; Cardiovascular and Genomics Research Institute, St George's School of Health and Medical Sciences, City St Georges University of London, London, United Kingdom.; Institute of Cardiovascular Science, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Humphries+SE%22">Humphries SE</searchLink>; Institute of Cardiovascular Science, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Chou+J%22">Chou J</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22März+W%22">März W</searchLink>; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.; Synlab MVZ Humangenetik Mannheim, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Geha+RS%22">Geha RS</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Shum+AK%22">Shum AK</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, U.S.A.<br /><searchLink fieldCode="AU" term="%22Kuivenhoven+JA%22">Kuivenhoven JA</searchLink>; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+de+Sluis+B%22">van de Sluis B</searchLink>; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22von+Eckardstein+A%22">von Eckardstein A</searchLink>; Institute for Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland.
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