Comparison of effectiveness and safety of cefoperazone-sulbactam versus ceftriaxone and flomoxef in acute cholangitis: a multicenter retrospective study.

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Title: Comparison of effectiveness and safety of cefoperazone-sulbactam versus ceftriaxone and flomoxef in acute cholangitis: a multicenter retrospective study.
Authors: Chen C-C; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan., Chen J-h; Division of Gastroenterology and Hepatology, Taipei Tzu Chi Hospital, New Taipei City, Taiwan.; School of Medicine, Tzu Chi University, Hualien, Taiwan., Huang W-H; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan., Hsieh T-L; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan., Chen L-W; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University at Keelung, Keelung, Taiwan., Tsai M-C; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Liu N-J; Department of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan., Wu C-H; Department of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan., Chung C-S; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.; Department of Electrical Engineering, Yuan Ze University, Taoyuan, Taiwan., Chiu Y-C; Division of Hepato-Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan., Liang C-M; Division of Hepato-Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan., Wu C-K; Division of Hepato-Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan., Wang W-L; Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan., Lee C-T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan., Hsu M-H; Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan., Wang H-P; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2026 Jul; Vol. 70 (7), pp. e0182925. Date of Electronic Publication: 2026 Jun 12.
Publication Type: Journal Article; Multicenter Study; Comparative Study
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comparison of effectiveness and safety of cefoperazone-sulbactam versus ceftriaxone and flomoxef in acute cholangitis: a multicenter retrospective study.
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  Data: <searchLink fieldCode="AU" term="%22Chen+C-C%22">Chen C-C</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+J-h%22">Chen J-h</searchLink>; Division of Gastroenterology and Hepatology, Taipei Tzu Chi Hospital, New Taipei City, Taiwan.; School of Medicine, Tzu Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+W-H%22">Huang W-H</searchLink>; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+T-L%22">Hsieh T-L</searchLink>; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+L-W%22">Chen L-W</searchLink>; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University at Keelung, Keelung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+M-C%22">Tsai M-C</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+N-J%22">Liu N-J</searchLink>; Department of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+C-H%22">Wu C-H</searchLink>; Department of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chung+C-S%22">Chung C-S</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.; Department of Electrical Engineering, Yuan Ze University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+Y-C%22">Chiu Y-C</searchLink>; Division of Hepato-Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liang+C-M%22">Liang C-M</searchLink>; Division of Hepato-Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+C-K%22">Wu C-K</searchLink>; Division of Hepato-Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+W-L%22">Wang W-L</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+C-T%22">Lee C-T</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+M-H%22">Hsu M-H</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+H-P%22">Wang H-P</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%220315061%22">Antimicrobial agents and chemotherapy</searchLink> [Antimicrob Agents Chemother] 2026 Jul; Vol. 70 (7), pp. e0182925. <i>Date of Electronic Publication: </i>2026 Jun 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0315061 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-6596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200664804%22">00664804 </searchLink><i>NLM ISO Abbreviation: </i>Antimicrob Agents Chemother <i>Subsets: </i>MEDLINE
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        Value: 10.1128/aac.01829-25
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        Text: English
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      – TitleFull: Comparison of effectiveness and safety of cefoperazone-sulbactam versus ceftriaxone and flomoxef in acute cholangitis: a multicenter retrospective study.
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              Text: 2026 Jul
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              Y: 2026
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