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SATB1 is a targetable modulator of JAK-STAT signaling and cytokines in human Treg and Tconv cells.

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Title: SATB1 is a targetable modulator of JAK-STAT signaling and cytokines in human Treg and Tconv cells.
Authors: Kolb S; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany., Diekmann L; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany.; Department of Biology, Immunology, University of Konstanz, Konstanz, Germany., Lochert EE; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany.; Technical University of Munich (TUM), School of Life Sciences, Department of Data Science of Systems Biology, Freising, Germany., Warmuth L; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany., Ritter J; Department of Biology, Immunology, University of Konstanz, Konstanz, Germany., Schmidtke G; Department of Biology, Immunology, University of Konstanz, Konstanz, Germany., Weber M; TUM, German Heart Center. Department of Anaesthiology, Munich, Germany., Hoffmann M; Technical University of Munich (TUM), School of Life Sciences, Department of Data Science of Systems Biology, Freising, Germany.; National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, MD, USA.; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, D.C., USA., List M; Technical University of Munich (TUM), School of Life Sciences, Department of Data Science of Systems Biology, Freising, Germany.; Technical University of Munich, Munich Data Science Institute (MDSI), Garching, Germany., Kotlarz D; Ludwig Maximilians University (LMU), Department of Pediatrics, Dr von Hauner Children's Hospital, University Hospital, Munich, Germany.; Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Child and Adolescent Health (DZKJ), partner site Munich, Munich, Germany., Serr I; Institute for Metabolism and Immunology, Helmholtz Diabetes Center at Helmholtz Munich, Munich, Germany.; German Center for Diabetes Research (DZD), Munich, Germany., Daniel C; Institute for Metabolism and Immunology, Helmholtz Diabetes Center at Helmholtz Munich, Munich, Germany.; German Center for Diabetes Research (DZD), Munich, Germany.; Institute of Clinical Pharmacology, LMU University Hospital, LMU Munich, Munich, Germany., Busch DH; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany.; German Center for Infection Research, Deutsches Zentrum für Infektionsforschung (DZIF), Partner Site Munich, Munich, Germany., Schmidl C; Epigenetic Immuno-oncology, Leibniz Institute for Immunotherapy, Regensburg, Germany., Schumann K; Department of Biology, Immunology, University of Konstanz, Konstanz, Germany. kathrin.schumann@uni-konstanz.de.
Source: EMBO reports [EMBO Rep] 2026 Jun 12. Date of Electronic Publication: 2026 Jun 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SATB1 is a targetable modulator of JAK-STAT signaling and cytokines in human Treg and Tconv cells.
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  Data: <searchLink fieldCode="AU" term="%22Kolb+S%22">Kolb S</searchLink>; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Diekmann+L%22">Diekmann L</searchLink>; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany.; Department of Biology, Immunology, University of Konstanz, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Lochert+EE%22">Lochert EE</searchLink>; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany.; Technical University of Munich (TUM), School of Life Sciences, Department of Data Science of Systems Biology, Freising, Germany.<br /><searchLink fieldCode="AU" term="%22Warmuth+L%22">Warmuth L</searchLink>; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ritter+J%22">Ritter J</searchLink>; Department of Biology, Immunology, University of Konstanz, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidtke+G%22">Schmidtke G</searchLink>; Department of Biology, Immunology, University of Konstanz, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+M%22">Weber M</searchLink>; TUM, German Heart Center. Department of Anaesthiology, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+M%22">Hoffmann M</searchLink>; Technical University of Munich (TUM), School of Life Sciences, Department of Data Science of Systems Biology, Freising, Germany.; National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, MD, USA.; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, D.C., USA.<br /><searchLink fieldCode="AU" term="%22List+M%22">List M</searchLink>; Technical University of Munich (TUM), School of Life Sciences, Department of Data Science of Systems Biology, Freising, Germany.; Technical University of Munich, Munich Data Science Institute (MDSI), Garching, Germany.<br /><searchLink fieldCode="AU" term="%22Kotlarz+D%22">Kotlarz D</searchLink>; Ludwig Maximilians University (LMU), Department of Pediatrics, Dr von Hauner Children's Hospital, University Hospital, Munich, Germany.; Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Child and Adolescent Health (DZKJ), partner site Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Serr+I%22">Serr I</searchLink>; Institute for Metabolism and Immunology, Helmholtz Diabetes Center at Helmholtz Munich, Munich, Germany.; German Center for Diabetes Research (DZD), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Daniel+C%22">Daniel C</searchLink>; Institute for Metabolism and Immunology, Helmholtz Diabetes Center at Helmholtz Munich, Munich, Germany.; German Center for Diabetes Research (DZD), Munich, Germany.; Institute of Clinical Pharmacology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Busch+DH%22">Busch DH</searchLink>; Technical University of Munich (TUM), School of Medicine and Health, Department of Preclinical Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany.; German Center for Infection Research, Deutsches Zentrum für Infektionsforschung (DZIF), Partner Site Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidl+C%22">Schmidl C</searchLink>; Epigenetic Immuno-oncology, Leibniz Institute for Immunotherapy, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schumann+K%22">Schumann K</searchLink>; Department of Biology, Immunology, University of Konstanz, Konstanz, Germany. kathrin.schumann@uni-konstanz.de.
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