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Fibronectin 1 mediates pressure-induced aggressive phenotypes in colorectal cancer cells and cancer stem cells.

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Title: Fibronectin 1 mediates pressure-induced aggressive phenotypes in colorectal cancer cells and cancer stem cells.
Authors: Nguyen VC; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Oncology Center, Hue Central Hospital, Hue, 530000, Viet Nam., Cheng KC; School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan., Phan TT; International Graduate Program, Chemical Biology and Molecular Biophysics, Academia Sinica, Taipei, 115, Taiwan.; Institute of Pharmaceutical Education and Research, Binh Duong University, Ho Chi Minh City, 700000, Viet Nam., Ho TL; Institute of Pharmaceutical Education and Research, Binh Duong University, Ho Chi Minh City, 700000, Viet Nam.; International Ph.D. Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan., Lin YH; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan., Kuo LJ; Division of Colorectal Surgery, Department of Surgery, Taipei Medical University Hospital, Taipei Medical University, Taipei, 110301, Taiwan. kuolijen@gmail.com.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. kuolijen@gmail.com., Shen YA; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. shen1202@tmu.edu.tw.; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. shen1202@tmu.edu.tw.; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. shen1202@tmu.edu.tw., Chen CL; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. chencl@tmu.edu.tw.; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. chencl@tmu.edu.tw.; Department of Pathology, Taipei Medical University Hospital, Taipei Medical University, Taipei, 110301, Taiwan. chencl@tmu.edu.tw.
Source: Cancer cell international [Cancer Cell Int] 2026 Jun 12. Date of Electronic Publication: 2026 Jun 12.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139795 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1475-2867 (Print) Linking ISSN: 14752867 NLM ISO Abbreviation: Cancer Cell Int
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  Data: Fibronectin 1 mediates pressure-induced aggressive phenotypes in colorectal cancer cells and cancer stem cells.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+VC%22">Nguyen VC</searchLink>; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Oncology Center, Hue Central Hospital, Hue, 530000, Viet Nam.<br /><searchLink fieldCode="AU" term="%22Cheng+KC%22">Cheng KC</searchLink>; School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.<br /><searchLink fieldCode="AU" term="%22Phan+TT%22">Phan TT</searchLink>; International Graduate Program, Chemical Biology and Molecular Biophysics, Academia Sinica, Taipei, 115, Taiwan.; Institute of Pharmaceutical Education and Research, Binh Duong University, Ho Chi Minh City, 700000, Viet Nam.<br /><searchLink fieldCode="AU" term="%22Ho+TL%22">Ho TL</searchLink>; Institute of Pharmaceutical Education and Research, Binh Duong University, Ho Chi Minh City, 700000, Viet Nam.; International Ph.D. Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YH%22">Lin YH</searchLink>; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+LJ%22">Kuo LJ</searchLink>; Division of Colorectal Surgery, Department of Surgery, Taipei Medical University Hospital, Taipei Medical University, Taipei, 110301, Taiwan. kuolijen@gmail.com.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. kuolijen@gmail.com.<br /><searchLink fieldCode="AU" term="%22Shen+YA%22">Shen YA</searchLink>; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. shen1202@tmu.edu.tw.; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. shen1202@tmu.edu.tw.; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. shen1202@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Chen+CL%22">Chen CL</searchLink>; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. chencl@tmu.edu.tw.; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. chencl@tmu.edu.tw.; Department of Pathology, Taipei Medical University Hospital, Taipei Medical University, Taipei, 110301, Taiwan. chencl@tmu.edu.tw.
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        Value: 10.1186/s12935-026-04381-5
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              Text: 2026 Jun 12
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