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Moderate iron restriction improves metabolism via epigenetic regulation of GDF15.

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Title: Moderate iron restriction improves metabolism via epigenetic regulation of GDF15.
Authors: Yang J; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA., Shi L; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA., Cubito AL; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA., Govarthanan A; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA., Sabripour JS; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA., Scott K; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA., de Kloet A; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA; Department of Physiology and Functional Genomics, College of Medicine, University of Florida, Gainesville, Florida, USA., Yue F; Department of Animal Sciences, University of Florida, Gainesville, Florida, USA., Liu B; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA., Strath LJ; Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, Florida, USA; Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, Florida, USA., Krause E; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA., Collins JF; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA., Cheng Z; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA. Electronic address: z.cheng@ufl.edu.
Source: The Journal of nutritional biochemistry [J Nutr Biochem] 2026 Nov; Vol. 157, pp. 110448. Date of Electronic Publication: 2026 Jun 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE
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  Data: Moderate iron restriction improves metabolism via epigenetic regulation of GDF15.
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  Data: <searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Shi+L%22">Shi L</searchLink>; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Cubito+AL%22">Cubito AL</searchLink>; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Govarthanan+A%22">Govarthanan A</searchLink>; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Sabripour+JS%22">Sabripour JS</searchLink>; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Scott+K%22">Scott K</searchLink>; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22de+Kloet+A%22">de Kloet A</searchLink>; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA; Department of Physiology and Functional Genomics, College of Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Yue+F%22">Yue F</searchLink>; Department of Animal Sciences, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Liu+B%22">Liu B</searchLink>; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Strath+LJ%22">Strath LJ</searchLink>; Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, Florida, USA; Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Krause+E%22">Krause E</searchLink>; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Collins+JF%22">Collins JF</searchLink>; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+Z%22">Cheng Z</searchLink>; Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; Nutritional Science Doctoral Program, Center for Nutritional Science, University of Florida, Gainesville, Florida, USA; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida, USA. Electronic address: z.cheng@ufl.edu.
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              Text: 2026 Nov
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