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Sirolimus-Eluting Balloon With Provisional Stenting Versus Systematic Drug-Eluting Stent Implantation to Treat De Novo Coronary Lesions: A Randomized, Open-Label, Noninferiority Trial.

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Title: Sirolimus-Eluting Balloon With Provisional Stenting Versus Systematic Drug-Eluting Stent Implantation to Treat De Novo Coronary Lesions: A Randomized, Open-Label, Noninferiority Trial.
Authors: Spaulding C; Department of Cardiology, European Hospital Georges Pompidou, Assistance Publique Hôpitaux de Paris, Paris-Cité University, INSERM Centre d'investigation Clinique 1414, France (C.S., E.P.)., Krackhardt F; Berlin Institute of Health at Charité Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Charité Campus Virchow-Klinikum, Germany (F.K)., Bogaerts K; Department of Public Health and Primary Care, I-BioStat, KU Leuven, Leuven and UHasselt, I-BioStat, Hasselt, Belgium (K.B.)., Abdelaal E; Manchester Heart Institute, Manchester University NHS Foundation Trust, UK (E.A.)., Alfonso F; Cardiology Department, Hospital Universitario de La Princesa/Universidad Autonoma de Madrid IIS-IP, CIBER-CV, Spain (F.A.)., Briguori C; Mediterranea Cardiocentro, Naples, Italy (C.B.)., Bruch L; BG Klinikum Unfallkrankenhaus Department of Internal Medicine/Cardiology, Berlin, Germany (L.B.)., Cruden N; Royal Infirmary of Edinburgh, UK (N.C.)., Den Hartog AW; Department of Cardiology, Amsterdam University Medical Center, Netherlands (A.W.D.H.)., Garot P; Institut Cardiovasculaire Paris Sud Hôpital Jacques Cartier Ramsay-Santé, Massy, France (P.G.)., Godin M; Clinique Saint Hillaire, Rouen, France (M.G.)., Hildick-Smith D; Sussex Cardiac Centre University Hospitals Sussex, Brighton, UK (D.H.-S.)., Johnson T; Bristol Heart Institute, Translational Health Sciences, University of Bristol, Bristol Royal Infirmary University, UK (T.J.)., Ladwiniec A; Department of Cardiovascular Sciences, University of Leicester, National Institute for Health and Care Research Leicester Biomedical Research Center, British Heart Foundation Centre of Research Excellence, Glenfield Hospital, UK (A.L.)., Linke A; Department of Internal Medicine and Cardiology, Herat Center, University Clinic, University of Technology Dresden, Germany (A.L.)., Maart CA; Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich Medical School, University of East Anglia, UK (C.A.M, S.E.)., Mashayekhi K; Department of Internal Medicine and Cardiology, Heart Center Lahr, Germany (K.M.)., Meier P; Service de Cardiologie, Fribourg Hospitals HFR, Switzerland (P.M.)., Meunier L; Cardiology Department, Centre Hospitalier La Rochelle, France (L.M.)., Morgan K; Northern General Hospital, Sheffield, UK (K.P.M.)., O'Kane P; Dorset Heart Centre, University Hospitals Dorset, Royal Bournemouth Hospital, UK (P.O.)., Puymirat E; Department of Cardiology, European Hospital Georges Pompidou, Assistance Publique Hôpitaux de Paris, Paris-Cité University, INSERM Centre d'investigation Clinique 1414, France (C.S., E.P.)., Rissanen TT; Heart Center, North Karelia Central Hospital, Siunsote, University of Eastern Finland, Kuopio (T.T.R.)., Sabaté M; Interventional Cardiology Department, Cardiovascular Institute, Hospital Clinic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, CIBER-CV, Barcelona, Spain (M.S.).; University of Barcelona, CIBER-CV, Spain (M.S.)., Schmitz T; Department of Cardiology, Elisabeth Krankenhaus Essen, Germany (T.S.)., Toth GG; Division of Cardiology, University Heart Center Graz, Medical University Graz, Germany (G.G.T.)., Trevelyan J; Worcestershire Acute Hospital NHS Trust, UK (J.T.)., Wanczura P; Department of Cardiology, Collegium Medicum, University of Rzeszow, Poland (P.W.)., Wiemer M; Johannes Wesling Universitätsklinik, Minden, Germany (M.W.)., Wykrzykowska JJ; Department of Cardiology, University Medical Center Groningen, Netherlands (J.W.)., Urban P; Cardiovascular Department, Hôpital de la Tour, Geneva, Switzerland (P.U.)., Eccleshall S; Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich Medical School, University of East Anglia, UK (C.A.M, S.E.).
Corporate Authors: SELUTION DeNovo Investigators
Source: Circulation [Circulation] 2026 Jul 21; Vol. 154 (3), pp. 185-197. Date of Electronic Publication: 2026 Jun 15.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Equivalence Trial; Comparative Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0147763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4539 (Electronic) Linking ISSN: 00097322 NLM ISO Abbreviation: Circulation Subsets: MEDLINE
Database: MEDLINE Ultimate
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Interventional Cardiology Department, Cardiovascular Institute, Hospital Clinic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, CIBER-CV, Barcelona, Spain (M.S.).; University of Barcelona, CIBER-CV, Spain (M.S.).<br /><searchLink fieldCode="AU" term="%22Schmitz+T%22">Schmitz T</searchLink>; Department of Cardiology, Elisabeth Krankenhaus Essen, Germany (T.S.).<br /><searchLink fieldCode="AU" term="%22Toth+GG%22">Toth GG</searchLink>; Division of Cardiology, University Heart Center Graz, Medical University Graz, Germany (G.G.T.).<br /><searchLink fieldCode="AU" term="%22Trevelyan+J%22">Trevelyan J</searchLink>; Worcestershire Acute Hospital NHS Trust, UK (J.T.).<br /><searchLink fieldCode="AU" term="%22Wanczura+P%22">Wanczura P</searchLink>; Department of Cardiology, Collegium Medicum, University of Rzeszow, Poland (P.W.).<br /><searchLink fieldCode="AU" term="%22Wiemer+M%22">Wiemer M</searchLink>; Johannes Wesling Universitätsklinik, Minden, Germany (M.W.).<br /><searchLink fieldCode="AU" term="%22Wykrzykowska+JJ%22">Wykrzykowska JJ</searchLink>; 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