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Glymphatic clearance as revealed by diffusion tensor imaging along the perivascular space (DTI-ALPS) is associated with Alzheimer's disease neuropathology and periodic rsEEG alpha rhythms in mild cognitive impairment participants.

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Title: Glymphatic clearance as revealed by diffusion tensor imaging along the perivascular space (DTI-ALPS) is associated with Alzheimer's disease neuropathology and periodic rsEEG alpha rhythms in mild cognitive impairment participants.
Authors: Lopez S; Department of Physiology and Pharmacology 'Vittorio Erspamer,' Sapienza University of Rome Rome Italy., Del Percio C; Department of Physiology and Pharmacology 'Vittorio Erspamer,' Sapienza University of Rome Rome Italy., Lizio R; Department of Physiology and Pharmacology 'Vittorio Erspamer,' Sapienza University of Rome Rome Italy.; Oasi Research Institute - IRCCS Troina Italy., Noce G; IRCCS Synlab SDN Naples Italy., Carpi M; Department of Physiology and Pharmacology 'Vittorio Erspamer,' Sapienza University of Rome Rome Italy., Arnaldi D; Dipartimento di Neuroscienze Oftalmologia, Genetica, Riabilitazione e Scienze Materno-infantili (DiNOGMI) Università di Genova Genova Italy.; IRCCS Ospedale Policlinico San Martino Genova Italy., Famà F; Dipartimento di Neuroscienze Oftalmologia, Genetica, Riabilitazione e Scienze Materno-infantili (DiNOGMI) Università di Genova Genova Italy.; IRCCS Ospedale Policlinico San Martino Genova Italy., Pardini M; Dipartimento di Neuroscienze Oftalmologia, Genetica, Riabilitazione e Scienze Materno-infantili (DiNOGMI) Università di Genova Genova Italy.; IRCCS Ospedale Policlinico San Martino Genova Italy., Massa F; Dipartimento di Neuroscienze Oftalmologia, Genetica, Riabilitazione e Scienze Materno-infantili (DiNOGMI) Università di Genova Genova Italy.; IRCCS Ospedale Policlinico San Martino Genova Italy., Marinozzi F; Department of Mechanical and Aerospace Engineering Sapienza University of Rome Rome Italy., Bini F; Department of Mechanical and Aerospace Engineering Sapienza University of Rome Rome Italy., Treves G; Department of Physiology and Pharmacology 'Vittorio Erspamer,' Sapienza University of Rome Rome Italy.; Department of Mechanical and Aerospace Engineering Sapienza University of Rome Rome Italy., Soricelli A; IRCCS Synlab SDN Naples Italy.; Department of Medical Movement and Well-being Sciences University of Naples Parthenope Naples Italy., Salvatore M; IRCCS Synlab SDN Naples Italy., Giubilei F; Department of Neuroscience Mental Health, and Sensory Organs Sapienza University of Rome Rome Italy., Ziccardi L; Department of Neuroscience Mental Health, and Sensory Organs Sapienza University of Rome Rome Italy., Güntekin B; Department of Biophysics School of Medicine Istanbul Medipol University İstanbul Turkey.; Research Institute for Health Sciences and Technologies (SABITA) Neuroscience Research Center Istanbul Medipol University İstanbul Turkey., Yener G; Department of Neurology Faculty of Medicine Dokuz Eylül University İzmir Turkey.; IBG: International Biomedicine and Genome Center İzmir Turkey., Ferri R; Oasi Research Institute - IRCCS Troina Italy., Lanuzza B; Oasi Research Institute - IRCCS Troina Italy., Stocchi F; IRCCS San Raffaele Roma Rome Italy.; San Raffaele Open University Rome Italy., Vacca L; IRCCS San Raffaele Roma Rome Italy., Coletti C; IRCCS San Raffaele Roma Rome Italy., Infarinato F; IRCCS San Raffaele Roma Rome Italy., Romano P; IRCCS San Raffaele Roma Rome Italy., Marizzoni M; Biological Psychiatry Unit IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli Brescia Italy., Frisoni GB; Memory Center Department of Rehabilitation and Geriatrics University Hospitals and University of Geneva Geneva Switzerland.; Laboratory of Neuroimaging of Aging (LANVIE) University of Geneva Geneva Switzerland., Barone P; Department of Medicine Surgery and Dentistry 'Scuola Medica Salernitana,' Neuroscience Section University of Salerno Baronissi Italy., Cappiello A; Department of Medicine Surgery and Dentistry 'Scuola Medica Salernitana,' Neuroscience Section University of Salerno Baronissi Italy., Cuoco S; Department of Medicine Surgery and Dentistry 'Scuola Medica Salernitana,' Neuroscience Section University of Salerno Baronissi Italy., Bonanni L; Department of Aging Medicine and Sciences University 'G. d'Annunzio' of Chieti-Pescara Chieti Italy., D'Anselmo A; Department of Aging Medicine and Sciences University 'G. d'Annunzio' of Chieti-Pescara Chieti Italy., Antonini A; IRCCS San Camillo Hospital Venice Italy.; Parkinson and Movement Disorders Unit, Study Center for Neurodegeneration (CESNE) Department of Neuroscience University of Padua Padua Italy., Fiorenzato E; Parkinson and Movement Disorders Unit, Study Center for Neurodegeneration (CESNE) Department of Neuroscience University of Padua Padua Italy., Cauzzo S; Department of Physiology and Pharmacology 'Vittorio Erspamer,' Sapienza University of Rome Rome Italy., Biundo R; Parkinson and Movement Disorders Unit, Study Center for Neurodegeneration (CESNE) Department of Neuroscience University of Padua Padua Italy.; Department of General Psychology University of Padua Padua Italy., D'Antonio F; Department of Human Neurosciences Sapienza University of Rome Rome Italy., De Pandis MF; IRCCS San Raffaele Roma, Cassino site Cassino Italy.; Department of Human Science and Promotion of Quality of Life San Raffaele Rome University Rome Italy., Marziali S; IRCCS San Raffaele Roma, Cassino site Cassino Italy., Bruno G; Department of Human Neurosciences Sapienza University of Rome Rome Italy., Carducci F; Department of Physiology and Pharmacology 'Vittorio Erspamer,' Sapienza University of Rome Rome Italy.; Oasi Research Institute - IRCCS Troina Italy., Babiloni C; Department of Physiology and Pharmacology 'Vittorio Erspamer,' Sapienza University of Rome Rome Italy.; Oasi Research Institute - IRCCS Troina Italy.; Dipartimento di Neuroscienze Oftalmologia, Genetica, Riabilitazione e Scienze Materno-infantili (DiNOGMI) Università di Genova Genova Italy.
Source: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2026 Jun 11; Vol. 18 (2), pp. e70384. Date of Electronic Publication: 2026 Jun 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101654604 Publication Model: eCollection Cited Medium: Print ISSN: 2352-8729 (Print) Linking ISSN: 23528729 NLM ISO Abbreviation: Alzheimers Dement (Amst) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Glymphatic clearance as revealed by diffusion tensor imaging along the perivascular space (DTI-ALPS) is associated with Alzheimer's disease neuropathology and periodic rsEEG alpha rhythms in mild cognitive impairment participants.
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