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Proof-of-principle 4-marker spatial profiling reveals distinct, location-independent immune clusters in biliary tract cancers.

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Title: Proof-of-principle 4-marker spatial profiling reveals distinct, location-independent immune clusters in biliary tract cancers.
Authors: Rossari F; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.; 'Vita-Salute' San Raffaele University, Milan, Italy., Sala M; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; University of Milan, Milan, Italy.; Politecnico di Milano, Milan, Italy., Rimini M; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.; 'Vita-Salute' San Raffaele University, Milan, Italy., Camera S; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Persano M; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Tonon G; 'Vita-Salute' San Raffaele University, Milan, Italy.; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy., Bonini C; 'Vita-Salute' San Raffaele University, Milan, Italy.; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Cangi MG; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Pecciarini L; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Doglioni C; 'Vita-Salute' San Raffaele University, Milan, Italy.; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ponzoni M; 'Vita-Salute' San Raffaele University, Milan, Italy.; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Balestrieri C; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Pedica F; 'Vita-Salute' San Raffaele University, Milan, Italy.; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Casadei-Gardini A; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.; 'Vita-Salute' San Raffaele University, Milan, Italy.
Source: Pathology oncology research : POR [Pathol Oncol Res] 2026 May 28; Vol. 32, pp. 1612389. Date of Electronic Publication: 2026 May 28 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 9706087 Publication Model: eCollection Cited Medium: Internet ISSN: 1532-2807 (Electronic) Linking ISSN: 12194956 NLM ISO Abbreviation: Pathol Oncol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Proof-of-principle 4-marker spatial profiling reveals distinct, location-independent immune clusters in biliary tract cancers.
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  Data: <searchLink fieldCode="AU" term="%22Rossari+F%22">Rossari F</searchLink>; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.; 'Vita-Salute' San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sala+M%22">Sala M</searchLink>; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; University of Milan, Milan, Italy.; Politecnico di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rimini+M%22">Rimini M</searchLink>; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.; 'Vita-Salute' San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Camera+S%22">Camera S</searchLink>; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Persano+M%22">Persano M</searchLink>; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tonon+G%22">Tonon G</searchLink>; 'Vita-Salute' San Raffaele University, Milan, Italy.; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bonini+C%22">Bonini C</searchLink>; 'Vita-Salute' San Raffaele University, Milan, Italy.; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cangi+MG%22">Cangi MG</searchLink>; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pecciarini+L%22">Pecciarini L</searchLink>; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Doglioni+C%22">Doglioni C</searchLink>; 'Vita-Salute' San Raffaele University, Milan, Italy.; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ponzoni+M%22">Ponzoni M</searchLink>; 'Vita-Salute' San Raffaele University, Milan, Italy.; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Balestrieri+C%22">Balestrieri C</searchLink>; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pedica+F%22">Pedica F</searchLink>; 'Vita-Salute' San Raffaele University, Milan, Italy.; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Casadei-Gardini+A%22">Casadei-Gardini A</searchLink>; Department of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.; 'Vita-Salute' San Raffaele University, Milan, Italy.
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  Data: <searchLink fieldCode="JN" term="%229706087%22">Pathology oncology research : POR</searchLink> [Pathol Oncol Res] 2026 May 28; Vol. 32, pp. 1612389. <i>Date of Electronic Publication: </i>2026 May 28 (<i>Print Publication: </i>2026).
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              Text: 2026 May 28
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