AlphaFold reveals how pathogenic Leptospira use cross-kingdom thiol-disulfide exchange to evade the complement membrane attack complex.

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Title: AlphaFold reveals how pathogenic Leptospira use cross-kingdom thiol-disulfide exchange to evade the complement membrane attack complex.
Authors: Hinds A; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom., Johnson E; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom.; Computational Biology Facility, LIV-SRF, MerseyBio, University of Liverpool, Liverpool, United Kingdom., Staton G; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom., Njume FN; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom., Crosby-Durrani HE; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom., Nally JE; Infectious Bacterial Disease Research Unit, National Animal Disease Centre, United States Department of Agriculture, Agricultural Research Service, Ames, Iowa, USA., Carter S; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom., Rigden DJ; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom., Evans NJ; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom.
Source: MBio [mBio] 2026 Jul 08; Vol. 17 (7), pp. e0087826. Date of Electronic Publication: 2026 Jun 15.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: AlphaFold reveals how pathogenic Leptospira use cross-kingdom thiol-disulfide exchange to evade the complement membrane attack complex.
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  Data: <searchLink fieldCode="AU" term="%22Hinds+A%22">Hinds A</searchLink>; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Johnson+E%22">Johnson E</searchLink>; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom.; Computational Biology Facility, LIV-SRF, MerseyBio, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Staton+G%22">Staton G</searchLink>; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Njume+FN%22">Njume FN</searchLink>; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Crosby-Durrani+HE%22">Crosby-Durrani HE</searchLink>; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nally+JE%22">Nally JE</searchLink>; Infectious Bacterial Disease Research Unit, National Animal Disease Centre, United States Department of Agriculture, Agricultural Research Service, Ames, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Carter+S%22">Carter S</searchLink>; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rigden+DJ%22">Rigden DJ</searchLink>; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Evans+NJ%22">Evans NJ</searchLink>; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Leahurst Campus, Chester, Neston, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%22101519231%22">MBio</searchLink> [mBio] 2026 Jul 08; Vol. 17 (7), pp. e0087826. <i>Date of Electronic Publication: </i>2026 Jun 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101519231 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2150-7511 (Electronic) <i>NLM ISO Abbreviation: </i>mBio <i>Subsets: </i>MEDLINE
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        Value: 10.1128/mbio.00878-26
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              Text: 2026 Jul 08
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