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Peripheral Immune Challenge Drives Enteric α-Synuclein and Tau Pathology in LRRK2 G2019S Mice.

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Title: Peripheral Immune Challenge Drives Enteric α-Synuclein and Tau Pathology in LRRK2 G2019S Mice.
Authors: Giachino C; Institut Imagine, INSERM UMR1163, Paris, France.; Neuropharmacology Laboratory, Oasi Research Institute-IRCCS, Troina, Italy.; Department of Biomedical and Biotechnological Sciences, Pharmacology Section, University of Catania, Italy., Bertoli F; Institut Imagine, INSERM UMR1163, Paris, France.; Mitochondria and Inflammation in Neurodegenerative Diseases, DZNE, Tübingen, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Germany., Tirolo C; Neuropharmacology Laboratory, Oasi Research Institute-IRCCS, Troina, Italy., Giuliano C; Mitochondria and Inflammation in Neurodegenerative Diseases, DZNE, Tübingen, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Germany., Mearelli M; Mitochondria and Inflammation in Neurodegenerative Diseases, DZNE, Tübingen, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Germany., Jakobi M; NMI Natural and Medical Sciences Institute, University of Tübingen, Reutlingen, Germany., Schneiderhan-Marra N; NMI Natural and Medical Sciences Institute, University of Tübingen, Reutlingen, Germany., L'Episcopo F; Neuropharmacology Laboratory, Oasi Research Institute-IRCCS, Troina, Italy., Deleidi M; Institut Imagine, INSERM UMR1163, Paris, France.; Mitochondria and Inflammation in Neurodegenerative Diseases, DZNE, Tübingen, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Germany.
Source: Aging and disease [Aging Dis] 2026 Jun 12. Date of Electronic Publication: 2026 Jun 12.
Publication Type: Journal Article
Journal Info: Publisher: JKL International Country of Publication: United States NLM ID: 101540533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2152-5250 (Electronic) Linking ISSN: 21525250 NLM ISO Abbreviation: Aging Dis Subsets: MEDLINE
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  Data: Peripheral Immune Challenge Drives Enteric α-Synuclein and Tau Pathology in LRRK2 G2019S Mice.
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  Data: <searchLink fieldCode="AU" term="%22Giachino+C%22">Giachino C</searchLink>; Institut Imagine, INSERM UMR1163, Paris, France.; Neuropharmacology Laboratory, Oasi Research Institute-IRCCS, Troina, Italy.; Department of Biomedical and Biotechnological Sciences, Pharmacology Section, University of Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Bertoli+F%22">Bertoli F</searchLink>; Institut Imagine, INSERM UMR1163, Paris, France.; Mitochondria and Inflammation in Neurodegenerative Diseases, DZNE, Tübingen, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Tirolo+C%22">Tirolo C</searchLink>; Neuropharmacology Laboratory, Oasi Research Institute-IRCCS, Troina, Italy.<br /><searchLink fieldCode="AU" term="%22Giuliano+C%22">Giuliano C</searchLink>; Mitochondria and Inflammation in Neurodegenerative Diseases, DZNE, Tübingen, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Mearelli+M%22">Mearelli M</searchLink>; Mitochondria and Inflammation in Neurodegenerative Diseases, DZNE, Tübingen, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Jakobi+M%22">Jakobi M</searchLink>; NMI Natural and Medical Sciences Institute, University of Tübingen, Reutlingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schneiderhan-Marra+N%22">Schneiderhan-Marra N</searchLink>; NMI Natural and Medical Sciences Institute, University of Tübingen, Reutlingen, Germany.<br /><searchLink fieldCode="AU" term="%22L'Episcopo+F%22">L'Episcopo F</searchLink>; Neuropharmacology Laboratory, Oasi Research Institute-IRCCS, Troina, Italy.<br /><searchLink fieldCode="AU" term="%22Deleidi+M%22">Deleidi M</searchLink>; Institut Imagine, INSERM UMR1163, Paris, France.; Mitochondria and Inflammation in Neurodegenerative Diseases, DZNE, Tübingen, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Germany.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22JKL+International%22">JKL International </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101540533 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2152-5250 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221525250%22">21525250 </searchLink><i>NLM ISO Abbreviation: </i>Aging Dis <i>Subsets: </i>MEDLINE
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        Value: 10.14336/AD.2026.0342
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        Text: English
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              Text: 2026 Jun 12
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