Effects of local heat on metabolic health, frailty risk, and exercise adaptations in pre-diabetic older adults: Protocol for the Heat and Exercise in Aging as Therapy (HEAT) clinical trial.

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Title: Effects of local heat on metabolic health, frailty risk, and exercise adaptations in pre-diabetic older adults: Protocol for the Heat and Exercise in Aging as Therapy (HEAT) clinical trial.
Authors: Luk HY; Applied Exercise Physiology Laboratory, Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, Texas, United States of America., Appell CR; Applied Exercise Physiology Laboratory, Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, Texas, United States of America., Zhang F; Department of Mathematics and Statistics, Texas Tech University, Lubbock, Texas, United States of America., Blinch J; Perception, Cognition, and Action Laboratory, Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, Texas, United States of America., Nair KS; Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, United States of America., Shen CL; Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America., Levitt DE; Metabolic Health and Muscle Physiology Laboratory, Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, Texas, United States of America.
Source: PloS one [PLoS One] 2026 Jun 15; Vol. 21 (6), pp. e0351577. Date of Electronic Publication: 2026 Jun 15 (Print Publication: 2026).
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effects of local heat on metabolic health, frailty risk, and exercise adaptations in pre-diabetic older adults: Protocol for the Heat and Exercise in Aging as Therapy (HEAT) clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Luk+HY%22">Luk HY</searchLink>; Applied Exercise Physiology Laboratory, Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Appell+CR%22">Appell CR</searchLink>; Applied Exercise Physiology Laboratory, Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Department of Mathematics and Statistics, Texas Tech University, Lubbock, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Blinch+J%22">Blinch J</searchLink>; Perception, Cognition, and Action Laboratory, Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Nair+KS%22">Nair KS</searchLink>; Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, United States of America.<br /><searchLink fieldCode="AU" term="%22Shen+CL%22">Shen CL</searchLink>; Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Levitt+DE%22">Levitt DE</searchLink>; Metabolic Health and Muscle Physiology Laboratory, Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, Texas, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Jun 15; Vol. 21 (6), pp. e0351577. <i>Date of Electronic Publication: </i>2026 Jun 15 (<i>Print Publication: </i>2026).
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