Long-term remission of neuromyelitis optica with allogeneic hematopoietic stem cell transplant.

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Title: Long-term remission of neuromyelitis optica with allogeneic hematopoietic stem cell transplant.
Authors: Orofino G; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy; 'Vita-Salute San Raffaele' University, Milano, Italy; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Genchi A; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neuroimmunology Unit, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milano, Italy., Lupo Stanghellini MT; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy; 'Vita-Salute San Raffaele' University, Milano, Italy., Doglio M; 'Vita-Salute San Raffaele' University, Milano, Italy; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy., Noviello M; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Cell Therapy Immunomonitoring Laboratory (MITiCi), Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Mandelli A; Clinical Neuroimmunology Unit, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milano, Italy., Vezzulli P; Department of Neuroradiology and CERMAC, IRCCS San Raffaele Scientific Institute, Milano, Italy., Valtolina V; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Cell Therapy Immunomonitoring Laboratory (MITiCi), Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Mastaglio S; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy., Piemontese S; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy., Tassi E; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Cell Therapy Immunomonitoring Laboratory (MITiCi), Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Ferrua F; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Hospital, Milano, Italy., Cicalese MP; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Hospital, Milano, Italy., Furlan R; 'Vita-Salute San Raffaele' University, Milano, Italy; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy; Clinical Neuroimmunology Unit, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milano, Italy., Martino G; 'Vita-Salute San Raffaele' University, Milano, Italy; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neuroimmunology Unit, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milano, Italy., Assanelli A; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy., Bernardi M; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy., Corti C; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy., Peccatori J; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy., Tortorelli F; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Toffalori C; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Vago L; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy; 'Vita-Salute San Raffaele' University, Milano, Italy; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Bonini C; 'Vita-Salute San Raffaele' University, Milano, Italy; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Cell Therapy Immunomonitoring Laboratory (MITiCi), Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Ciceri F; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy; 'Vita-Salute San Raffaele' University, Milano, Italy. Electronic address: ciceri.fabio@hsr.it., Filippi M; 'Vita-Salute San Raffaele' University, Milano, Italy; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neurorehabilitation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neurophysiology Service, IRCCS San Raffaele Scientific Institute, Milano, Italy. Electronic address: filippi.massimo@hsr.it., Moiola L; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy., Greco R; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.
Source: Med (New York, N.Y.) [Med] 2026 Jul 10; Vol. 7 (7), pp. 101179. Date of Electronic Publication: 2026 Jun 15.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6340 (Electronic) Linking ISSN: 26666340 NLM ISO Abbreviation: Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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Items – Name: Title
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  Data: Long-term remission of neuromyelitis optica with allogeneic hematopoietic stem cell transplant.
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  Data: <searchLink fieldCode="AU" term="%22Orofino+G%22">Orofino G</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy; 'Vita-Salute San Raffaele' University, Milano, Italy; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Genchi+A%22">Genchi A</searchLink>; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neuroimmunology Unit, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Lupo+Stanghellini+MT%22">Lupo Stanghellini MT</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy; 'Vita-Salute San Raffaele' University, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Doglio+M%22">Doglio M</searchLink>; 'Vita-Salute San Raffaele' University, Milano, Italy; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Noviello+M%22">Noviello M</searchLink>; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Cell Therapy Immunomonitoring Laboratory (MITiCi), Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Mandelli+A%22">Mandelli A</searchLink>; Clinical Neuroimmunology Unit, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Vezzulli+P%22">Vezzulli P</searchLink>; Department of Neuroradiology and CERMAC, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Valtolina+V%22">Valtolina V</searchLink>; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Cell Therapy Immunomonitoring Laboratory (MITiCi), Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Mastaglio+S%22">Mastaglio S</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Piemontese+S%22">Piemontese S</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Tassi+E%22">Tassi E</searchLink>; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Cell Therapy Immunomonitoring Laboratory (MITiCi), Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrua+F%22">Ferrua F</searchLink>; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Hospital, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Cicalese+MP%22">Cicalese MP</searchLink>; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Hospital, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Furlan+R%22">Furlan R</searchLink>; 'Vita-Salute San Raffaele' University, Milano, Italy; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy; Clinical Neuroimmunology Unit, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Martino+G%22">Martino G</searchLink>; 'Vita-Salute San Raffaele' University, Milano, Italy; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neuroimmunology Unit, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Assanelli+A%22">Assanelli A</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Bernardi+M%22">Bernardi M</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Corti+C%22">Corti C</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Peccatori+J%22">Peccatori J</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Tortorelli+F%22">Tortorelli F</searchLink>; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Toffalori+C%22">Toffalori C</searchLink>; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Vago+L%22">Vago L</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy; 'Vita-Salute San Raffaele' University, Milano, Italy; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Bonini+C%22">Bonini C</searchLink>; 'Vita-Salute San Raffaele' University, Milano, Italy; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy; Cell Therapy Immunomonitoring Laboratory (MITiCi), Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Ciceri+F%22">Ciceri F</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy; 'Vita-Salute San Raffaele' University, Milano, Italy. Electronic address: ciceri.fabio@hsr.it.<br /><searchLink fieldCode="AU" term="%22Filippi+M%22">Filippi M</searchLink>; 'Vita-Salute San Raffaele' University, Milano, Italy; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neurorehabilitation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy; Neurophysiology Service, IRCCS San Raffaele Scientific Institute, Milano, Italy. Electronic address: filippi.massimo@hsr.it.<br /><searchLink fieldCode="AU" term="%22Moiola+L%22">Moiola L</searchLink>; Neurology Department, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Greco+R%22">Greco R</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.
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