Prognostic and therapeutic implications of BRAF mutations in acute myeloid leukemia.
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| Title: | Prognostic and therapeutic implications of BRAF mutations in acute myeloid leukemia. |
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| Authors: | Lee D; University of Cincinnati College of Medicine, Cincinnati, OH, USA., Abu-Shihab Y; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Plas K; University of Cincinnati, Computational Science Graduate Program, Cincinnati, OH, USA., Nicolet D; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Mrózek K; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Routbort MJ; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA., Patel KP; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA., Walker CJ; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Buss J; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Stiff AR; Department of Internal Medicine, Ohio State University, Columbus, OH, USA., Laganson A; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., DiNardo CD; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA., Daver NG; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA., Kadia TM; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA., Ravandi F; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA., Carroll AJ; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA., Kolitz JE; Northwell Cancer Center, Hofstra/Northwell School of Medicine, Lake Success, NY, USA., Powell BL; Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC, USA., Blum WG; Winship Cancer Institute of Emory University School of Medicine, Atlanta, GA, USA., Baer MR; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA., Marcucci G; Department of Hematology, City of Hope Comprehensive Cancer, Duarte, CA, USA., Uy GL; Division of Oncology, Washington University School of Medicine, Saint Louis, MO, USA., Stock W; University of Chicago Medicine, Chicago, IL, USA., Stone RM; Dana-Farber Cancer Institute, Boston, MA, USA., Medeiros LJ; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA., Byrd JC; University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.; University of Cincinnati Cancer Center, Cincinnati, OH, USA., Blachly JS; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Bowman RL; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Tyner JW; Department of Cell, Developmental & Cancer Biology, Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR, USA., Loghavi S; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA. sloghavi@mdanderson.org., Eisfeld AK; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. ann-kathrin.eisfeld@osumc.edu.; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. ann-kathrin.eisfeld@osumc.edu., Miles LA; University of Cincinnati Cancer Center, Cincinnati, OH, USA. linde.miles@cchmc.org.; Division of Experimental Hematology & Cancer Biology, Cancer & Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. linde.miles@cchmc.org.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA. linde.miles@cchmc.org. |
| Source: | Leukemia [Leukemia] 2026 Jun 15. Date of Electronic Publication: 2026 Jun 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42297916 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prognostic and therapeutic implications of BRAF mutations in acute myeloid leukemia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lee+D%22">Lee D</searchLink>; University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Abu-Shihab+Y%22">Abu-Shihab Y</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Plas+K%22">Plas K</searchLink>; University of Cincinnati, Computational Science Graduate Program, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Nicolet+D%22">Nicolet D</searchLink>; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Mrózek+K%22">Mrózek K</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Routbort+MJ%22">Routbort MJ</searchLink>; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Patel+KP%22">Patel KP</searchLink>; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Walker+CJ%22">Walker CJ</searchLink>; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Buss+J%22">Buss J</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Stiff+AR%22">Stiff AR</searchLink>; Department of Internal Medicine, Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Laganson+A%22">Laganson A</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22DiNardo+CD%22">DiNardo CD</searchLink>; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Daver+NG%22">Daver NG</searchLink>; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kadia+TM%22">Kadia TM</searchLink>; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ravandi+F%22">Ravandi F</searchLink>; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Carroll+AJ%22">Carroll AJ</searchLink>; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Kolitz+JE%22">Kolitz JE</searchLink>; Northwell Cancer Center, Hofstra/Northwell School of Medicine, Lake Success, NY, USA.<br /><searchLink fieldCode="AU" term="%22Powell+BL%22">Powell BL</searchLink>; Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Blum+WG%22">Blum WG</searchLink>; Winship Cancer Institute of Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Baer+MR%22">Baer MR</searchLink>; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Marcucci+G%22">Marcucci G</searchLink>; Department of Hematology, City of Hope Comprehensive Cancer, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Uy+GL%22">Uy GL</searchLink>; Division of Oncology, Washington University School of Medicine, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Stock+W%22">Stock W</searchLink>; University of Chicago Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Stone+RM%22">Stone RM</searchLink>; Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Medeiros+LJ%22">Medeiros LJ</searchLink>; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Byrd+JC%22">Byrd JC</searchLink>; University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.; University of Cincinnati Cancer Center, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Blachly+JS%22">Blachly JS</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Bowman+RL%22">Bowman RL</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tyner+JW%22">Tyner JW</searchLink>; Department of Cell, Developmental & Cancer Biology, Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Loghavi+S%22">Loghavi S</searchLink>; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA. sloghavi@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Eisfeld+AK%22">Eisfeld AK</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. ann-kathrin.eisfeld@osumc.edu.; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. ann-kathrin.eisfeld@osumc.edu.<br /><searchLink fieldCode="AU" term="%22Miles+LA%22">Miles LA</searchLink>; University of Cincinnati Cancer Center, Cincinnati, OH, USA. linde.miles@cchmc.org.; Division of Experimental Hematology & Cancer Biology, Cancer & Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. linde.miles@cchmc.org.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA. linde.miles@cchmc.org. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2026 Jun 15. <i>Date of Electronic Publication: </i>2026 Jun 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%2C+Specialist+Journals%22">Nature Publishing Group, Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8704895 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208876924%22">08876924 </searchLink><i>NLM ISO Abbreviation: </i>Leukemia <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42297916 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41375-026-02996-1 Languages: – Code: eng Text: English Titles: – TitleFull: Prognostic and therapeutic implications of BRAF mutations in acute myeloid leukemia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lee D – PersonEntity: Name: NameFull: Abu-Shihab Y – PersonEntity: Name: NameFull: Plas K – PersonEntity: Name: NameFull: Nicolet D – PersonEntity: Name: NameFull: Mrózek K – PersonEntity: Name: NameFull: Routbort MJ – PersonEntity: Name: NameFull: Patel KP – PersonEntity: Name: NameFull: Walker CJ – PersonEntity: Name: NameFull: Buss J – PersonEntity: Name: NameFull: Stiff AR – PersonEntity: Name: NameFull: Laganson A – PersonEntity: Name: NameFull: DiNardo CD – PersonEntity: Name: NameFull: Daver NG – PersonEntity: Name: NameFull: Kadia TM – PersonEntity: Name: NameFull: Ravandi F – PersonEntity: Name: NameFull: Carroll AJ – PersonEntity: Name: NameFull: Kolitz JE – PersonEntity: Name: NameFull: Powell BL – PersonEntity: Name: NameFull: Blum WG – PersonEntity: Name: NameFull: Baer MR – PersonEntity: Name: NameFull: Marcucci G – PersonEntity: Name: NameFull: Uy GL – PersonEntity: Name: NameFull: Stock W – PersonEntity: Name: NameFull: Stone RM – PersonEntity: Name: NameFull: Medeiros LJ – PersonEntity: Name: NameFull: Byrd JC – PersonEntity: Name: NameFull: Blachly JS – PersonEntity: Name: NameFull: Bowman RL – PersonEntity: Name: NameFull: Tyner JW – PersonEntity: Name: NameFull: Loghavi S – PersonEntity: Name: NameFull: Eisfeld AK – PersonEntity: Name: NameFull: Miles LA IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 06 Text: 2026 Jun 15 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1476-5551 Titles: – TitleFull: Leukemia Type: main |
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