Amphiregulin drives EGFR-dependent genome stability in colorectal cancer and represents a targetable vulnerability.
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| Title: | Amphiregulin drives EGFR-dependent genome stability in colorectal cancer and represents a targetable vulnerability. |
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| Authors: | Park SJ; Department of Physiology, Jeonbuk National University Medical School, Jeonju, Republic of Korea., Lee SW; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea.; School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea., Moon H; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea., Jung SM; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea.; School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea., Kim JM; Department of Pathology, Konyang University College of Medicine, Daejeon, Republic of Korea., Lee DS; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea. lee1@knu.ac.kr.; School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea. lee1@knu.ac.kr., Choi EH; Department of Biotechnology, Korea National University of Transportation, Chungbuk, Republic of Korea. ehchoi@ut.ac.kr. |
| Source: | Oncogene [Oncogene] 2026 Aug; Vol. 45 (29), pp. 2914-2931. Date of Electronic Publication: 2026 Jun 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42298179 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Amphiregulin drives EGFR-dependent genome stability in colorectal cancer and represents a targetable vulnerability. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Park+SJ%22">Park SJ</searchLink>; Department of Physiology, Jeonbuk National University Medical School, Jeonju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SW%22">Lee SW</searchLink>; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea.; School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+H%22">Moon H</searchLink>; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+SM%22">Jung SM</searchLink>; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea.; School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JM%22">Kim JM</searchLink>; Department of Pathology, Konyang University College of Medicine, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+DS%22">Lee DS</searchLink>; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea. lee1@knu.ac.kr.; School of Life Sciences & Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea. lee1@knu.ac.kr.<br /><searchLink fieldCode="AU" term="%22Choi+EH%22">Choi EH</searchLink>; Department of Biotechnology, Korea National University of Transportation, Chungbuk, Republic of Korea. ehchoi@ut.ac.kr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2026 Aug; Vol. 45 (29), pp. 2914-2931. <i>Date of Electronic Publication: </i>2026 Jun 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8711562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5594 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209509232%22">09509232 </searchLink><i>NLM ISO Abbreviation: </i>Oncogene <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42298179 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41388-026-03850-5 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2914 Titles: – TitleFull: Amphiregulin drives EGFR-dependent genome stability in colorectal cancer and represents a targetable vulnerability. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Park SJ – PersonEntity: Name: NameFull: Lee SW – PersonEntity: Name: NameFull: Moon H – PersonEntity: Name: NameFull: Jung SM – PersonEntity: Name: NameFull: Kim JM – PersonEntity: Name: NameFull: Lee DS – PersonEntity: Name: NameFull: Choi EH IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: 2026 Aug Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1476-5594 Numbering: – Type: volume Value: 45 – Type: issue Value: 29 Titles: – TitleFull: Oncogene Type: main |
| ResultId | 1 |