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Toxicity assessment in preclinical histopathology via class-aware Mahalanobis distance for known and novel anomalies.

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Title: Toxicity assessment in preclinical histopathology via class-aware Mahalanobis distance for known and novel anomalies.
Authors: Graf O; Tübingen AI Center, University of Tübingen, Tübingen, Germany. olga.graf@uni-tuebingen.de., Patel D; Toxicologic Pathologist, Gujarat, India., Groß P; Boehringer Ingelheim Pharma GmbH and Co., Biberach an der Riß, Germany., Lempp C; Boehringer Ingelheim Pharma GmbH and Co., Biberach an der Riß, Germany., Hein M; Tübingen AI Center, University of Tübingen, Tübingen, Germany., Heinemann F; Boehringer Ingelheim GmbH, Biberach an der Riß, Germany.
Source: Scientific reports [Sci Rep] 2026 Jun 17; Vol. 16 (1). Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Graf+O%22">Graf O</searchLink>; Tübingen AI Center, University of Tübingen, Tübingen, Germany. olga.graf@uni-tuebingen.de.<br /><searchLink fieldCode="AU" term="%22Patel+D%22">Patel D</searchLink>; Toxicologic Pathologist, Gujarat, India.<br /><searchLink fieldCode="AU" term="%22Groß+P%22">Groß P</searchLink>; Boehringer Ingelheim Pharma GmbH and Co., Biberach an der Riß, Germany.<br /><searchLink fieldCode="AU" term="%22Lempp+C%22">Lempp C</searchLink>; Boehringer Ingelheim Pharma GmbH and Co., Biberach an der Riß, Germany.<br /><searchLink fieldCode="AU" term="%22Hein+M%22">Hein M</searchLink>; Tübingen AI Center, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Heinemann+F%22">Heinemann F</searchLink>; Boehringer Ingelheim GmbH, Biberach an der Riß, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Jun 17; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Jun 17.
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        Value: 10.1038/s41598-026-56510-9
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              Text: 2026 Jun 17
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