Molecular-level insights into the therapeutic potential of lidocaine: effects on proliferation, autophagy, and cellular impedance in human oral cells.

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Title: Molecular-level insights into the therapeutic potential of lidocaine: effects on proliferation, autophagy, and cellular impedance in human oral cells.
Authors: Huang WZ; Department of Dentistry, Tri-Service General Hospital, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China.; Department of Mechanical Engineering, National Central University, Taoyuan City, 320, Taiwan, Republic of China., Chen GS; Department of Dentistry, Tri-Service General Hospital, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China.; School of Dentistry, College of Oral Medicine, National Defense Medical University, Taipei City 114, Taiwan, Republic of China., Liu ST; Institute of Biochemistry, College of Biomedical Sciences, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China., Lee SP; Department of Dentistry, Tri-Service General Hospital, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China.; School of Dentistry, College of Oral Medicine, National Defense Medical University, Taipei City 114, Taiwan, Republic of China., Huang SM; Institute of Biochemistry, College of Biomedical Sciences, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China., Chen JL; Department of Anesthesiology, School of Medicine, College of Medicine, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China. babe.ane@gmail.com.; Department of Anesthesiology, Tri-Service General Hospital, National Defense Medical University, Taipei City 114, Taiwan, Republic of China. babe.ane@gmail.com.
Source: BMC oral health [BMC Oral Health] 2026 Jun 16. Date of Electronic Publication: 2026 Jun 16.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088684 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-6831 (Electronic) Linking ISSN: 14726831 NLM ISO Abbreviation: BMC Oral Health Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Molecular-level insights into the therapeutic potential of lidocaine: effects on proliferation, autophagy, and cellular impedance in human oral cells.
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  Data: <searchLink fieldCode="AU" term="%22Huang+WZ%22">Huang WZ</searchLink>; Department of Dentistry, Tri-Service General Hospital, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China.; Department of Mechanical Engineering, National Central University, Taoyuan City, 320, Taiwan, Republic of China.<br /><searchLink fieldCode="AU" term="%22Chen+GS%22">Chen GS</searchLink>; Department of Dentistry, Tri-Service General Hospital, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China.; School of Dentistry, College of Oral Medicine, National Defense Medical University, Taipei City 114, Taiwan, Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+ST%22">Liu ST</searchLink>; Institute of Biochemistry, College of Biomedical Sciences, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China.<br /><searchLink fieldCode="AU" term="%22Lee+SP%22">Lee SP</searchLink>; Department of Dentistry, Tri-Service General Hospital, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China.; School of Dentistry, College of Oral Medicine, National Defense Medical University, Taipei City 114, Taiwan, Republic of China.<br /><searchLink fieldCode="AU" term="%22Huang+SM%22">Huang SM</searchLink>; Institute of Biochemistry, College of Biomedical Sciences, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China.<br /><searchLink fieldCode="AU" term="%22Chen+JL%22">Chen JL</searchLink>; Department of Anesthesiology, School of Medicine, College of Medicine, National Defense Medical University, Taipei City, 114, Taiwan, Republic of China. babe.ane@gmail.com.; Department of Anesthesiology, Tri-Service General Hospital, National Defense Medical University, Taipei City 114, Taiwan, Republic of China. babe.ane@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101088684%22">BMC oral health</searchLink> [BMC Oral Health] 2026 Jun 16. <i>Date of Electronic Publication: </i>2026 Jun 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101088684 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1472-6831 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214726831%22">14726831 </searchLink><i>NLM ISO Abbreviation: </i>BMC Oral Health <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1186/s12903-026-08877-4
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      – Code: eng
        Text: English
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      – TitleFull: Molecular-level insights into the therapeutic potential of lidocaine: effects on proliferation, autophagy, and cellular impedance in human oral cells.
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            NameFull: Huang WZ
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            NameFull: Chen GS
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            – D: 16
              M: 06
              Text: 2026 Jun 16
              Type: published
              Y: 2026
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              Value: 1472-6831
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