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Bone marrow immunosuppressive states associate with survival after guadecitabine and atezolizumab therapy in HMA-R/R MDS.

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Title: Bone marrow immunosuppressive states associate with survival after guadecitabine and atezolizumab therapy in HMA-R/R MDS.
Authors: Jang HJ; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.; Department of Cell Biology, Van Andel Institute, Grand Rapids, MI., Urrutia G; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI., Ørskov AD; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Biotech Research & Innovation Center, University of Copenhagen, Copenhagen, Denmark., Nguyen AV; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI., Kim HJ; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI., Nelson SA; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI., Lee H; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI., Burgos RS; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI., Johnson BK; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI., Wegener M; Genomics Core, Van Andel Institute, Grand Rapids, MI., Becker K; Genomics Core, Van Andel Institute, Grand Rapids, MI., Adams M; Genomics Core, Van Andel Institute, Grand Rapids, MI., Sheridan R; Flow Cytometry Core, Van Andel Institute, Grand Rapids, MI., Ramjan ZH; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI., Givan SA; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI., Zebley CC; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN.; Department of Bone Marrow Transplantation & Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN., Youngblood BA; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN., Issa JJ; Coriell Institute for Medical Research, Camden, NJ., Topper MJ; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD., Baylin SB; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD., Baer MR; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD., Triche TJ Jr; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI., O'Connell CL; Jane Anne Nohl Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA., Grønbæk K; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Biotech Research & Innovation Center, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jones PA; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.
Source: Blood neoplasia [Blood Neoplasia] 2026 May 05; Vol. 3 (3), pp. 100243. Date of Electronic Publication: 2026 May 05 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918841988906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2950-3280 (Electronic) Linking ISSN: 29503280 NLM ISO Abbreviation: Blood Neoplasia Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Bone marrow immunosuppressive states associate with survival after guadecitabine and atezolizumab therapy in HMA-R/R MDS.
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  Data: <searchLink fieldCode="AU" term="%22Jang+HJ%22">Jang HJ</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.; Department of Cell Biology, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Urrutia+G%22">Urrutia G</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Ørskov+AD%22">Ørskov AD</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Biotech Research & Innovation Center, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Nguyen+AV%22">Nguyen AV</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Nelson+SA%22">Nelson SA</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Burgos+RS%22">Burgos RS</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Johnson+BK%22">Johnson BK</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Wegener+M%22">Wegener M</searchLink>; Genomics Core, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Becker+K%22">Becker K</searchLink>; Genomics Core, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Adams+M%22">Adams M</searchLink>; Genomics Core, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Sheridan+R%22">Sheridan R</searchLink>; Flow Cytometry Core, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Ramjan+ZH%22">Ramjan ZH</searchLink>; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Givan+SA%22">Givan SA</searchLink>; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22Zebley+CC%22">Zebley CC</searchLink>; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN.; Department of Bone Marrow Transplantation & Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN.<br /><searchLink fieldCode="AU" term="%22Youngblood+BA%22">Youngblood BA</searchLink>; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN.<br /><searchLink fieldCode="AU" term="%22Issa+JJ%22">Issa JJ</searchLink>; Coriell Institute for Medical Research, Camden, NJ.<br /><searchLink fieldCode="AU" term="%22Topper+MJ%22">Topper MJ</searchLink>; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Baylin+SB%22">Baylin SB</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Baer+MR%22">Baer MR</searchLink>; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Triche+TJ+Jr%22">Triche TJ Jr</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.<br /><searchLink fieldCode="AU" term="%22O'Connell+CL%22">O'Connell CL</searchLink>; Jane Anne Nohl Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Grønbæk+K%22">Grønbæk K</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Biotech Research & Innovation Center, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Jones+PA%22">Jones PA</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI.
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  Data: <searchLink fieldCode="JN" term="%229918841988906676%22">Blood neoplasia</searchLink> [Blood Neoplasia] 2026 May 05; Vol. 3 (3), pp. 100243. <i>Date of Electronic Publication: </i>2026 May 05 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2C+Inc%22">Elsevier, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918841988906676 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2950-3280 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2229503280%22">29503280 </searchLink><i>NLM ISO Abbreviation: </i>Blood Neoplasia <i>Subsets: </i>PubMed not MEDLINE
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