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A toxic STING-SAMHD1 axis drives replication stress in progeria and cancer cells.

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Title: A toxic STING-SAMHD1 axis drives replication stress in progeria and cancer cells.
Authors: Teodoro-Castro B; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States., de Faria RC; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States., Shashkova EV; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States., Malique A; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States., Adolph MB; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States., Silva LND; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States., Gonzalo S; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States.
Source: Nucleic acids research [Nucleic Acids Res] 2026 Jun 08; Vol. 54 (11).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Teodoro-Castro+B%22">Teodoro-Castro B</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States.<br /><searchLink fieldCode="AU" term="%22de+Faria+RC%22">de Faria RC</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States.<br /><searchLink fieldCode="AU" term="%22Shashkova+EV%22">Shashkova EV</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States.<br /><searchLink fieldCode="AU" term="%22Malique+A%22">Malique A</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States.<br /><searchLink fieldCode="AU" term="%22Adolph+MB%22">Adolph MB</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States.<br /><searchLink fieldCode="AU" term="%22Silva+LND%22">Silva LND</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States.<br /><searchLink fieldCode="AU" term="%22Gonzalo+S%22">Gonzalo S</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, United States.
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        Value: 10.1093/nar/gkag614
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              Text: 2026 Jun 08
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