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Gene therapy in patients with choroideremia: a meta-analysis of clinical trials.

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Title: Gene therapy in patients with choroideremia: a meta-analysis of clinical trials.
Authors: Redruello-Guerrero P; Department of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain. predruello@saludcastillayleon.es.; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain. predruello@saludcastillayleon.es.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain. predruello@saludcastillayleon.es., Ridruejo-Ortega B; Department of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., González-Barros D; Department of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Silva-Schultz S; Department of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Stalmashka T; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain., Molinero-Sicilia L; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain.; Department of Cell Biology, Genetics, Histology, and Pharmacology, Faculty of Medicine, University of Valladolid, Valladolid, Spain., Benites-Narcizo G; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain.; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, USA., Rivera-Izquierdo M; Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain.; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain., Usategui-Martín R; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain.; Department of Cell Biology, Genetics, Histology, and Pharmacology, Faculty of Medicine, University of Valladolid, Valladolid, Spain.; Unit of Excellence Instituto Universitario de Oftalmobiologia Aplicada (IOBA), Universidad de Valladolid, Valladolid, Spain., Pastor-Idoate S; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain. salvador.pastor@uva.es.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain. salvador.pastor@uva.es.; Unit of Excellence Instituto Universitario de Oftalmobiologia Aplicada (IOBA), Universidad de Valladolid, Valladolid, Spain. salvador.pastor@uva.es.; Department of Ophthalmology, Member of the European Reference Network for Rare Eye Diseases (ERN-EYE), Hospital Clínico Universitario de Valladolid, Valladolid, Spain. salvador.pastor@uva.es.
Source: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie [Graefes Arch Clin Exp Ophthalmol] 2026 Jun 17. Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 8205248 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-702X (Electronic) Linking ISSN: 0721832X NLM ISO Abbreviation: Graefes Arch Clin Exp Ophthalmol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Redruello-Guerrero+P%22">Redruello-Guerrero P</searchLink>; Department of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain. predruello@saludcastillayleon.es.; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain. predruello@saludcastillayleon.es.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain. predruello@saludcastillayleon.es.<br /><searchLink fieldCode="AU" term="%22Ridruejo-Ortega+B%22">Ridruejo-Ortega B</searchLink>; Department of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22González-Barros+D%22">González-Barros D</searchLink>; Department of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Silva-Schultz+S%22">Silva-Schultz S</searchLink>; Department of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Stalmashka+T%22">Stalmashka T</searchLink>; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Molinero-Sicilia+L%22">Molinero-Sicilia L</searchLink>; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain.; Department of Cell Biology, Genetics, Histology, and Pharmacology, Faculty of Medicine, University of Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Benites-Narcizo+G%22">Benites-Narcizo G</searchLink>; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain.; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, USA.<br /><searchLink fieldCode="AU" term="%22Rivera-Izquierdo+M%22">Rivera-Izquierdo M</searchLink>; Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain.; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Usategui-Martín+R%22">Usategui-Martín R</searchLink>; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain.; Department of Cell Biology, Genetics, Histology, and Pharmacology, Faculty of Medicine, University of Valladolid, Valladolid, Spain.; Unit of Excellence Instituto Universitario de Oftalmobiologia Aplicada (IOBA), Universidad de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Pastor-Idoate+S%22">Pastor-Idoate S</searchLink>; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Campus Miguel Delibes, P.º de Belén, 17, Valladolid, 47011, Spain. salvador.pastor@uva.es.; Networks of Cooperative Research Oriented to Health Results (RICORS), National Institute of Health Carlos III (ISCIII), Madrid, Spain. salvador.pastor@uva.es.; Unit of Excellence Instituto Universitario de Oftalmobiologia Aplicada (IOBA), Universidad de Valladolid, Valladolid, Spain. salvador.pastor@uva.es.; Department of Ophthalmology, Member of the European Reference Network for Rare Eye Diseases (ERN-EYE), Hospital Clínico Universitario de Valladolid, Valladolid, Spain. salvador.pastor@uva.es.
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              Text: 2026 Jun 17
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