Deep learning-enabled discovery of antibiotics effective against Neisseria gonorrhoeae.
Saved in:
| Title: | Deep learning-enabled discovery of antibiotics effective against Neisseria gonorrhoeae. |
|---|---|
| Authors: | Anahtar MN; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Departments of Pathology and Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Valeri JA; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Modaresi SM; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Krishnan A; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Donghia NM; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA., Palace SG; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Zheng EJ; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.; Program in Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Gulati A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA., Jorgenson A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA., Junaid A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA., Bandyopadhyay P; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Luttens A; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Suresh K; Harvard Medical School, Boston, MA 02115, USA., Edwards P; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Wong F; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Integrated Biosciences Inc., Redwood City, CA 94065, USA., Zhang Y; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Ritz D; Proteomics Core Facility, Biozentrum, University of Basel, Basel CH-4056, Switzerland., Gaborieau M; Department of Microbiology, Tumor, and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden., Loh E; Department of Microbiology, Tumor, and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden.; Clinical Microbiology, Karolinska University Hospital, 171 76 Stockholm, Sweden., Gaetani M; Division of Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institute, 17 177 Stockholm, Sweden.; Chemical Proteomics Unit, Science for Life Laboratory (SciLifeLab), 171 77 Stockholm, Sweden., Aschtgen MS; Department of Microbiology, Tumor, and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden., Saei AA; Department of Microbiology, Tumor, and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden., Grad YH; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Ingber DE; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.; Vascular Biology Program and Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Harvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA 02539, USA., Collins JJ; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2026 Jun 17; Vol. 18 (854), pp. eads4699. Date of Electronic Publication: 2026 Jun 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
Be the first to leave a comment!
