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Effects on hippocampal activity following novel 5-HT4 receptor agonism in unmedicated patients with depression: the RESTAND study.

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Title: Effects on hippocampal activity following novel 5-HT4 receptor agonism in unmedicated patients with depression: the RESTAND study.
Authors: de Cates AN; Institute for Mental Health, University of Birmingham, Edgbaston, Birmingham, UK. a.n.decates@bham.ac.uk.; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK. a.n.decates@bham.ac.uk., Gillespie AL; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK., Scaife J; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK., Martens MAG; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK., Carson J; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK., Godlewska BR; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK., Howard W; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK., Guru A; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK., Cowen PJ; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK., Harmer CJ; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.; Oxford Centre for Human Brain Activity, Oxford Centre for Integrative Neuroimaging, Department of Psychiatry, University of Oxford, Oxford, UK., Murphy SE; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
Source: Translational psychiatry [Transl Psychiatry] 2026 Jun 17. Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22de+Cates+AN%22">de Cates AN</searchLink>; Institute for Mental Health, University of Birmingham, Edgbaston, Birmingham, UK. a.n.decates@bham.ac.uk.; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK. a.n.decates@bham.ac.uk.<br /><searchLink fieldCode="AU" term="%22Gillespie+AL%22">Gillespie AL</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Scaife+J%22">Scaife J</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Martens+MAG%22">Martens MAG</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Carson+J%22">Carson J</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Godlewska+BR%22">Godlewska BR</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Howard+W%22">Howard W</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Guru+A%22">Guru A</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Cowen+PJ%22">Cowen PJ</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Harmer+CJ%22">Harmer CJ</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.; Oxford Centre for Human Brain Activity, Oxford Centre for Integrative Neuroimaging, Department of Psychiatry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Murphy+SE%22">Murphy SE</searchLink>; University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
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              Text: 2026 Jun 17
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