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Exploiting androgen receptor agonism as a treatment strategy in estrogen receptor-positive metastatic breast cancer.

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Title: Exploiting androgen receptor agonism as a treatment strategy in estrogen receptor-positive metastatic breast cancer.
Authors: Monserrat L; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; University of Barcelona (UB), Barcelona, Spain., García-García J; Molecular Biology Institute of Barcelona, Consejo Superior de Investigaciones Científicas (IBMB-CSIC), Barcelona, Spain., Molina C; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Òdena A; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; University of Barcelona (UB), Barcelona, Spain., Yuziv Duda T; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Agustí-Barea I; Bioinformatics Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Flamen G; Bioinformatics Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Viaplana C; Oncology Data Science Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Nagornyuk A; Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA., Maldonado-Padrol R; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Yáñez-Bartolomé C; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Pedretti F; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Guzmán M; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Rodríguez O; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Brasó-Maristany F; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Clínic Barcelona Comprehensive Cancer Center, Hospital Clinic of Barcelona, Barcelona, Spain., García-Galea E; Oncology Data Science Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Dienstmann R; Oncology Data Science Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; University of Vic, Central University of Catalonia, Vic, Spain., Takaku M; Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA., Prat A; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Clínic Barcelona Comprehensive Cancer Center, Hospital Clinic of Barcelona, Barcelona, Spain., Chandarlapaty S; Departments of Pathology and Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, NY, USA., Ponomarenko J; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Saura C; Vall d'Hebron Hospital and Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Oliveira M; Vall d'Hebron Hospital and Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Nonell L; Bioinformatics Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Bellet M; Vall d'Hebron Hospital and Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. mbellet@vhio.net., Vicent GP; Molecular Biology Institute of Barcelona, Consejo Superior de Investigaciones Científicas (IBMB-CSIC), Barcelona, Spain. gvmbmc@ibmb.csic.es., Serra V; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. vserra@vhio.net.
Source: NPJ breast cancer [NPJ Breast Cancer] 2026 Jun 17. Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: Breast Cancer Research Foundation Country of Publication: United States NLM ID: 101674891 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2374-4677 (Print) Linking ISSN: 23744677 NLM ISO Abbreviation: NPJ Breast Cancer
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  Data: Exploiting androgen receptor agonism as a treatment strategy in estrogen receptor-positive metastatic breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Monserrat+L%22">Monserrat L</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; University of Barcelona (UB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22García-García+J%22">García-García J</searchLink>; Molecular Biology Institute of Barcelona, Consejo Superior de Investigaciones Científicas (IBMB-CSIC), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Molina+C%22">Molina C</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Òdena+A%22">Òdena A</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; University of Barcelona (UB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Yuziv+Duda+T%22">Yuziv Duda T</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Agustí-Barea+I%22">Agustí-Barea I</searchLink>; Bioinformatics Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Flamen+G%22">Flamen G</searchLink>; Bioinformatics Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Viaplana+C%22">Viaplana C</searchLink>; Oncology Data Science Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Nagornyuk+A%22">Nagornyuk A</searchLink>; Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA.<br /><searchLink fieldCode="AU" term="%22Maldonado-Padrol+R%22">Maldonado-Padrol R</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Yáñez-Bartolomé+C%22">Yáñez-Bartolomé C</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pedretti+F%22">Pedretti F</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Guzmán+M%22">Guzmán M</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez+O%22">Rodríguez O</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Brasó-Maristany+F%22">Brasó-Maristany F</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Clínic Barcelona Comprehensive Cancer Center, Hospital Clinic of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22García-Galea+E%22">García-Galea E</searchLink>; Oncology Data Science Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Dienstmann+R%22">Dienstmann R</searchLink>; Oncology Data Science Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; University of Vic, Central University of Catalonia, Vic, Spain.<br /><searchLink fieldCode="AU" term="%22Takaku+M%22">Takaku M</searchLink>; Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA.<br /><searchLink fieldCode="AU" term="%22Prat+A%22">Prat A</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Clínic Barcelona Comprehensive Cancer Center, Hospital Clinic of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Chandarlapaty+S%22">Chandarlapaty S</searchLink>; Departments of Pathology and Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ponomarenko+J%22">Ponomarenko J</searchLink>; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Saura+C%22">Saura C</searchLink>; Vall d'Hebron Hospital and Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Oliveira+M%22">Oliveira M</searchLink>; Vall d'Hebron Hospital and Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Nonell+L%22">Nonell L</searchLink>; Bioinformatics Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bellet+M%22">Bellet M</searchLink>; Vall d'Hebron Hospital and Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. mbellet@vhio.net.<br /><searchLink fieldCode="AU" term="%22Vicent+GP%22">Vicent GP</searchLink>; Molecular Biology Institute of Barcelona, Consejo Superior de Investigaciones Científicas (IBMB-CSIC), Barcelona, Spain. gvmbmc@ibmb.csic.es.<br /><searchLink fieldCode="AU" term="%22Serra+V%22">Serra V</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. vserra@vhio.net.
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