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Molecular basis of polyadenylated RNA fate determination in the nucleus.

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Title: Molecular basis of polyadenylated RNA fate determination in the nucleus.
Authors: Bugai A; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Hohmann U; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biology, Mainz, Germany., Lorenzo A; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Graf M; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, Austria., Fin L; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Rouvière JO; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Tirian L; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Dou Y; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland., Le Rest M; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Polák P; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Johnsen D; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Jakobsen L; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark., Andersen JS; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark., Brennecke J; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria. julius.brennecke@imba.oeaw.ac.at., Plaschka C; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. clemens.plaschka@imp.ac.at., Jensen TH; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. thj@mbg.au.dk.
Source: Nature [Nature] 2026 Jul; Vol. 655 (8124), pp. 1070-1078. Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: Molecular basis of polyadenylated RNA fate determination in the nucleus.
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  Data: <searchLink fieldCode="AU" term="%22Bugai+A%22">Bugai A</searchLink>; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Hohmann+U%22">Hohmann U</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biology, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Lorenzo+A%22">Lorenzo A</searchLink>; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Graf+M%22">Graf M</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Fin+L%22">Fin L</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Rouvière+JO%22">Rouvière JO</searchLink>; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Tirian+L%22">Tirian L</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Dou+Y%22">Dou Y</searchLink>; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Le+Rest+M%22">Le Rest M</searchLink>; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Polák+P%22">Polák P</searchLink>; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Johnsen+D%22">Johnsen D</searchLink>; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Jakobsen+L%22">Jakobsen L</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark.<br /><searchLink fieldCode="AU" term="%22Andersen+JS%22">Andersen JS</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark.<br /><searchLink fieldCode="AU" term="%22Brennecke+J%22">Brennecke J</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria. julius.brennecke@imba.oeaw.ac.at.<br /><searchLink fieldCode="AU" term="%22Plaschka+C%22">Plaschka C</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. clemens.plaschka@imp.ac.at.<br /><searchLink fieldCode="AU" term="%22Jensen+TH%22">Jensen TH</searchLink>; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. thj@mbg.au.dk.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 Jul; Vol. 655 (8124), pp. 1070-1078. <i>Date of Electronic Publication: </i>2026 Jun 17.
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        Value: 10.1038/s41586-026-10650-0
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              Text: 2026 Jul
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