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Proposal for Circadian Rhythms and Their Behavioral Outputs as Biomarkers in DSM-6: Response to Cuthbert et al.

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Title: Proposal for Circadian Rhythms and Their Behavioral Outputs as Biomarkers in DSM-6: Response to Cuthbert et al.
Authors: Crouse JJ; Brain and Mind Centre, University of Sydney, Sydney, Australia., Carpenter JS; Brain and Mind Centre, University of Sydney, Sydney, Australia., Burns AC; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston.; Division of Sleep Medicine, Harvard Medical School, Boston., Henriksen TEG; Division of Mental Health Care, Valen Hospital, Department of Research and Innovation, Fonna Health Trust, Kvinnherad, Norway., McCarthy MJ; Department of Psychiatry, University of California San Diego, San Diego., Merikangas KR; Genetic Epidemiology Branch, National Institute of Mental Health, Bethesda, MD., Meyer N; Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London., Scott J; Academic Psychiatry, Institute of Neuroscience, Newcastle University, Newcastle, UK., Shin M; Brain and Mind Centre, University of Sydney, Sydney, Australia., Smith DJ; Division of Psychiatry, University of Edinburgh, Edinburgh., Swartz HA; Department of Psychiatry, University of Pittsburgh, Pittsburgh., Tonini E; Brain and Mind Centre, University of Sydney, Sydney, Australia., Zarate CA Jr; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, Bethesda, MD., Hickie IB; Brain and Mind Centre, University of Sydney, Sydney, Australia.
Source: The American journal of psychiatry [Am J Psychiatry] 2026 Jun 18, pp. appiajp20260227. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Letter
Journal Info: Publisher: American Psychiatric Association Country of Publication: United States NLM ID: 0370512 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-7228 (Electronic) Linking ISSN: 0002953X NLM ISO Abbreviation: Am J Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Editorial & Opinion
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  Data: Proposal for Circadian Rhythms and Their Behavioral Outputs as Biomarkers in DSM-6: Response to Cuthbert et al.
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  Data: <searchLink fieldCode="AU" term="%22Crouse+JJ%22">Crouse JJ</searchLink>; Brain and Mind Centre, University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Carpenter+JS%22">Carpenter JS</searchLink>; Brain and Mind Centre, University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Burns+AC%22">Burns AC</searchLink>; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston.; Division of Sleep Medicine, Harvard Medical School, Boston.<br /><searchLink fieldCode="AU" term="%22Henriksen+TEG%22">Henriksen TEG</searchLink>; Division of Mental Health Care, Valen Hospital, Department of Research and Innovation, Fonna Health Trust, Kvinnherad, Norway.<br /><searchLink fieldCode="AU" term="%22McCarthy+MJ%22">McCarthy MJ</searchLink>; Department of Psychiatry, University of California San Diego, San Diego.<br /><searchLink fieldCode="AU" term="%22Merikangas+KR%22">Merikangas KR</searchLink>; Genetic Epidemiology Branch, National Institute of Mental Health, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Meyer+N%22">Meyer N</searchLink>; Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London.<br /><searchLink fieldCode="AU" term="%22Scott+J%22">Scott J</searchLink>; Academic Psychiatry, Institute of Neuroscience, Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Shin+M%22">Shin M</searchLink>; Brain and Mind Centre, University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Smith+DJ%22">Smith DJ</searchLink>; Division of Psychiatry, University of Edinburgh, Edinburgh.<br /><searchLink fieldCode="AU" term="%22Swartz+HA%22">Swartz HA</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh.<br /><searchLink fieldCode="AU" term="%22Tonini+E%22">Tonini E</searchLink>; Brain and Mind Centre, University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Zarate+CA+Jr%22">Zarate CA Jr</searchLink>; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Hickie+IB%22">Hickie IB</searchLink>; Brain and Mind Centre, University of Sydney, Sydney, Australia.
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  Data: <searchLink fieldCode="JN" term="%220370512%22">The American journal of psychiatry</searchLink> [Am J Psychiatry] 2026 Jun 18, pp. appiajp20260227. <i>Date of Electronic Publication: </i>2026 Jun 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Psychiatric+Association%22">American Psychiatric Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370512 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-7228 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220002953X%22">0002953X </searchLink><i>NLM ISO Abbreviation: </i>Am J Psychiatry <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 18
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