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Simvastatin Treatment in Patients with Liver Cirrhosis: a Phase II Randomized Placebo Controlled Trial Shows Reduction in IL-6 Levels.

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Title: Simvastatin Treatment in Patients with Liver Cirrhosis: a Phase II Randomized Placebo Controlled Trial Shows Reduction in IL-6 Levels.
Authors: Hussain SK; UC Davis Comprehensive Cancer Center Sacramento, California United States., Ayoub WS; Cedars-Sinai Medical Center Los Angeles, California United States., Cruz-Correa M; University of Puerto Rico, Medical Sciences Campus San Juan, PR Puerto Rico., Kulik LM; Northwestern Medical Faculty Foundation Chicago, IL United States., Smith C; MedStar Georgetown University Hospital United States., Rodriguez LM; National Cancer Institute Rockville, md United States., Richmond E; National Cancer Institute Bethesda, MD United States., Umar A; National Cancer Institute Rockville, MD United States., Davey S; Cedars-Sinai Medical Center United States., Benante K; Northwestern University Feinberg School of Medicine Chicago, IL United States., Schering T; Northwestern University Feinberg School of Medicine Chicago, IL United States., Kocherginsky M; Northwestern University Feinberg School of Medicine Chicago, Il United States., Chen R; Northwestern University Feinberg School of Medicine Chicago, IL United States., Mi X; Northwestern University Feinberg School of Medicine Chicago, IL United States., Khan SA; Northwestern University Feinberg School of Medicine Chicago, IL United States., Goodman MT; Cedars-Sinai Medical Center Los Angeles, California United States.
Source: Cancer prevention research (Philadelphia, Pa.) [Cancer Prev Res (Phila)] 2026 Jun 17. Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101479409 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1940-6215 (Electronic) Linking ISSN: 19406215 NLM ISO Abbreviation: Cancer Prev Res (Phila) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Simvastatin Treatment in Patients with Liver Cirrhosis: a Phase II Randomized Placebo Controlled Trial Shows Reduction in IL-6 Levels.
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  Data: <searchLink fieldCode="AU" term="%22Hussain+SK%22">Hussain SK</searchLink>; UC Davis Comprehensive Cancer Center Sacramento, California United States.<br /><searchLink fieldCode="AU" term="%22Ayoub+WS%22">Ayoub WS</searchLink>; Cedars-Sinai Medical Center Los Angeles, California United States.<br /><searchLink fieldCode="AU" term="%22Cruz-Correa+M%22">Cruz-Correa M</searchLink>; University of Puerto Rico, Medical Sciences Campus San Juan, PR Puerto Rico.<br /><searchLink fieldCode="AU" term="%22Kulik+LM%22">Kulik LM</searchLink>; Northwestern Medical Faculty Foundation Chicago, IL United States.<br /><searchLink fieldCode="AU" term="%22Smith+C%22">Smith C</searchLink>; MedStar Georgetown University Hospital United States.<br /><searchLink fieldCode="AU" term="%22Rodriguez+LM%22">Rodriguez LM</searchLink>; National Cancer Institute Rockville, md United States.<br /><searchLink fieldCode="AU" term="%22Richmond+E%22">Richmond E</searchLink>; National Cancer Institute Bethesda, MD United States.<br /><searchLink fieldCode="AU" term="%22Umar+A%22">Umar A</searchLink>; National Cancer Institute Rockville, MD United States.<br /><searchLink fieldCode="AU" term="%22Davey+S%22">Davey S</searchLink>; Cedars-Sinai Medical Center United States.<br /><searchLink fieldCode="AU" term="%22Benante+K%22">Benante K</searchLink>; Northwestern University Feinberg School of Medicine Chicago, IL United States.<br /><searchLink fieldCode="AU" term="%22Schering+T%22">Schering T</searchLink>; Northwestern University Feinberg School of Medicine Chicago, IL United States.<br /><searchLink fieldCode="AU" term="%22Kocherginsky+M%22">Kocherginsky M</searchLink>; Northwestern University Feinberg School of Medicine Chicago, Il United States.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Northwestern University Feinberg School of Medicine Chicago, IL United States.<br /><searchLink fieldCode="AU" term="%22Mi+X%22">Mi X</searchLink>; Northwestern University Feinberg School of Medicine Chicago, IL United States.<br /><searchLink fieldCode="AU" term="%22Khan+SA%22">Khan SA</searchLink>; Northwestern University Feinberg School of Medicine Chicago, IL United States.<br /><searchLink fieldCode="AU" term="%22Goodman+MT%22">Goodman MT</searchLink>; Cedars-Sinai Medical Center Los Angeles, California United States.
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  Data: <searchLink fieldCode="JN" term="%22101479409%22">Cancer prevention research (Philadelphia, Pa.)</searchLink> [Cancer Prev Res (Phila)] 2026 Jun 17. <i>Date of Electronic Publication: </i>2026 Jun 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101479409 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1940-6215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219406215%22">19406215 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Prev Res (Phila) <i>Subsets: </i>MEDLINE
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        Value: 10.1158/1940-6207.CAPR-25-0241
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        Text: English
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      – TitleFull: Simvastatin Treatment in Patients with Liver Cirrhosis: a Phase II Randomized Placebo Controlled Trial Shows Reduction in IL-6 Levels.
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              Text: 2026 Jun 17
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