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Matrix type influences embedded patient-derived osteosarcoma organoid invasion and response to treatment.

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Title: Matrix type influences embedded patient-derived osteosarcoma organoid invasion and response to treatment.
Authors: Hipwood L; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.; Centre for Biomedical Technologies, Queensland University of Technology, Brisbane, QLD, Australia.; Gelomics Pty Ltd., Brisbane, QLD, Australia.; Translational Research Institute (TRI), Brisbane, QLD, Australia.; Max Planck Queensland Centre (MPQC) for the Materials Science of Extracellular Matrices, Queensland University of Technology, Brisbane, Australia., Vargas Reyes DM; Gelomics Pty Ltd., Brisbane, QLD, Australia.; The University of Queensland, Brisbane, QLD, Australia., Thompson EW; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.; Translational Research Institute (TRI), Brisbane, QLD, Australia.; Centre for Genomics and Personalised Health, QUT, Brisbane, QLD, Australia., Rowell PD; Orthopaedics Department, Princess Alexandra Hospital, Metro South Hospital and Health Services, Brisbane, QLD, Australia., Lowe M; Orthopaedics Department, Princess Alexandra Hospital, Metro South Hospital and Health Services, Brisbane, QLD, Australia., Nicholls W; Oncology Services Group, Children's Health Queensland Hospital and Health Servies, Queensland Children's Hospital, Brisbane, QLD, Australia., Bhatia S; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.; Centre for Biomedical Technologies, Queensland University of Technology, Brisbane, QLD, Australia.; Translational Research Institute (TRI), Brisbane, QLD, Australia., Hutmacher DW; Gelomics Pty Ltd., Brisbane, QLD, Australia.; Max Planck Queensland Centre (MPQC) for the Materials Science of Extracellular Matrices, Queensland University of Technology, Brisbane, Australia., Meinert C; Gelomics Pty Ltd., Brisbane, QLD, Australia., McGovern JA; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.; Centre for Biomedical Technologies, Queensland University of Technology, Brisbane, QLD, Australia.; Translational Research Institute (TRI), Brisbane, QLD, Australia.; Max Planck Queensland Centre (MPQC) for the Materials Science of Extracellular Matrices, Queensland University of Technology, Brisbane, Australia.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 Jun 02; Vol. 17, pp. 1831729. Date of Electronic Publication: 2026 Jun 02 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hipwood+L%22">Hipwood L</searchLink>; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.; Centre for Biomedical Technologies, Queensland University of Technology, Brisbane, QLD, Australia.; Gelomics Pty Ltd., Brisbane, QLD, Australia.; Translational Research Institute (TRI), Brisbane, QLD, Australia.; Max Planck Queensland Centre (MPQC) for the Materials Science of Extracellular Matrices, Queensland University of Technology, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Vargas+Reyes+DM%22">Vargas Reyes DM</searchLink>; Gelomics Pty Ltd., Brisbane, QLD, Australia.; The University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Thompson+EW%22">Thompson EW</searchLink>; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.; Translational Research Institute (TRI), Brisbane, QLD, Australia.; Centre for Genomics and Personalised Health, QUT, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Rowell+PD%22">Rowell PD</searchLink>; Orthopaedics Department, Princess Alexandra Hospital, Metro South Hospital and Health Services, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Lowe+M%22">Lowe M</searchLink>; Orthopaedics Department, Princess Alexandra Hospital, Metro South Hospital and Health Services, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Nicholls+W%22">Nicholls W</searchLink>; Oncology Services Group, Children's Health Queensland Hospital and Health Servies, Queensland Children's Hospital, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Bhatia+S%22">Bhatia S</searchLink>; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.; Centre for Biomedical Technologies, Queensland University of Technology, Brisbane, QLD, Australia.; Translational Research Institute (TRI), Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Hutmacher+DW%22">Hutmacher DW</searchLink>; Gelomics Pty Ltd., Brisbane, QLD, Australia.; Max Planck Queensland Centre (MPQC) for the Materials Science of Extracellular Matrices, Queensland University of Technology, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Meinert+C%22">Meinert C</searchLink>; Gelomics Pty Ltd., Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22McGovern+JA%22">McGovern JA</searchLink>; Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.; Centre for Biomedical Technologies, Queensland University of Technology, Brisbane, QLD, Australia.; Translational Research Institute (TRI), Brisbane, QLD, Australia.; Max Planck Queensland Centre (MPQC) for the Materials Science of Extracellular Matrices, Queensland University of Technology, Brisbane, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2026 Jun 02; Vol. 17, pp. 1831729. <i>Date of Electronic Publication: </i>2026 Jun 02 (<i>Print Publication: </i>2026).
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              Text: 2026 Jun 02
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