Age and early life adversity shape heterogeneity of the epigenome across tissues in macaques.
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| Title: | Age and early life adversity shape heterogeneity of the epigenome across tissues in macaques. |
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| Authors: | Sadoughi B; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA., Petersen RM; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA., Patterson SK; Department of Anthropology, New York University, New York, NY, USA.; New York Consortium in Evolutionary Primatology, New York, NY, USA.; Department of Anthropology, University of Notre Dame, South Bend, IN, USA., Slikas E; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA., Adjangba C; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA., Ryan N; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA., Costa CE; Department of Anthropology, New York University, New York, NY, USA.; New York Consortium in Evolutionary Primatology, New York, NY, USA., Newman LE; Department of Anthropology, New York University, New York, NY, USA.; New York Consortium in Evolutionary Primatology, New York, NY, USA., Watowich MM; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA., Kelsey CR; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA., Greenier A; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA., Goldman EA; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA., Negrón-Del Valle JE; School of Life Sciences, Arizona State University, Tempe, AZ, USA., Phillips D; School of Life Sciences, Arizona State University, Tempe, AZ, USA., Thompson I; Center for Anatomical Sciences, University of North Texas Health Science Center, Fort Worth, TX, USA., Bauman Surratt SE; Caribbean Primate Research Center, University of Puerto Rico, Punta Santiago, Puerto Rico., González O; Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA., Compo N; Caribbean Primate Research Center, University of Puerto Rico, Punta Santiago, Puerto Rico., Burgos A; Caribbean Primate Research Center, University of Puerto Rico, Punta Santiago, Puerto Rico., DeCasien AR; Computational and Evolutionary Neurogenomics Unit, Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, MD, USA., Chiou KL; Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Walker CS; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA., Ruiz Lambides AV; Caribbean Primate Research Center, University of Puerto Rico, Punta Santiago, Puerto Rico., Martínez MI; Caribbean Primate Research Center, University of Puerto Rico, Punta Santiago, Puerto Rico., Sterner KN; Department of Anthropology, University of Oregon, Eugene, OR, USA., Melin AD; Department of Anthropology and Archaeology, University of Calgary, Calgary, AB, Canada.; Department of Medical Genetics, University of Calgary, Calgary, AB, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada., Brent LJN; Centre for Research in Animal Behaviour, University of Exeter, Exeter, UK., Higham JP; Department of Anthropology, New York University, New York, NY, USA.; New York Consortium in Evolutionary Primatology, New York, NY, USA., Montague MJ; Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA., Platt ML; Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA., Snyder-Mackler N; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.; School for Human Evolution and Social Change, Arizona State University, Tempe, AZ, USA., Lea AJ; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA., Antón SC, Brent LJN, Higham JP, Martínez MI, Melin AD, Montague MJ, Platt ML, Sallet J, Snyder-Mackler N |
| Corporate Authors: | Cayo Biobank Research Unit‡, Cayo Biobank Research Unit |
| Source: | Science (New York, N.Y.) [Science] 2026 Jun 18; Vol. 392 (6804), pp. eaea4922. Date of Electronic Publication: 2026 Jun 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42313974 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Age and early life adversity shape heterogeneity of the epigenome across tissues in macaques. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sadoughi+B%22">Sadoughi B</searchLink>; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Petersen+RM%22">Petersen RM</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Patterson+SK%22">Patterson SK</searchLink>; Department of Anthropology, New York University, New York, NY, USA.; New York Consortium in Evolutionary Primatology, New York, NY, USA.; Department of Anthropology, University of Notre Dame, South Bend, IN, USA.<br /><searchLink fieldCode="AU" term="%22Slikas+E%22">Slikas E</searchLink>; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Adjangba+C%22">Adjangba C</searchLink>; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Ryan+N%22">Ryan N</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Costa+CE%22">Costa CE</searchLink>; Department of Anthropology, New York University, New York, NY, USA.; New York Consortium in Evolutionary Primatology, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Newman+LE%22">Newman LE</searchLink>; Department of Anthropology, New York University, New York, NY, USA.; New York Consortium in Evolutionary Primatology, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Watowich+MM%22">Watowich MM</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Kelsey+CR%22">Kelsey CR</searchLink>; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Greenier+A%22">Greenier A</searchLink>; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Goldman+EA%22">Goldman EA</searchLink>; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Negrón-Del+Valle+JE%22">Negrón-Del Valle JE</searchLink>; School of Life Sciences, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Phillips+D%22">Phillips D</searchLink>; School of Life Sciences, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+I%22">Thompson I</searchLink>; Center for Anatomical Sciences, University of North Texas Health Science Center, Fort Worth, TX, USA.<br /><searchLink fieldCode="AU" term="%22Bauman+Surratt+SE%22">Bauman Surratt SE</searchLink>; 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Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ruiz+Lambides+AV%22">Ruiz Lambides AV</searchLink>; Caribbean Primate Research Center, University of Puerto Rico, Punta Santiago, Puerto Rico.<br /><searchLink fieldCode="AU" term="%22Martínez+MI%22">Martínez MI</searchLink>; Caribbean Primate Research Center, University of Puerto Rico, Punta Santiago, Puerto Rico.<br /><searchLink fieldCode="AU" term="%22Sterner+KN%22">Sterner KN</searchLink>; Department of Anthropology, University of Oregon, Eugene, OR, USA.<br /><searchLink fieldCode="AU" term="%22Melin+AD%22">Melin AD</searchLink>; Department of Anthropology and Archaeology, University of Calgary, Calgary, AB, Canada.; Department of Medical Genetics, University of Calgary, Calgary, AB, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Brent+LJN%22">Brent LJN</searchLink>; Centre for Research in Animal Behaviour, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Higham+JP%22">Higham JP</searchLink>; Department of Anthropology, New York University, New York, NY, USA.; New York Consortium in Evolutionary Primatology, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Montague+MJ%22">Montague MJ</searchLink>; Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Platt+ML%22">Platt ML</searchLink>; Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Snyder-Mackler+N%22">Snyder-Mackler N</searchLink>; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, USA.; School for Human Evolution and Social Change, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Lea+AJ%22">Lea AJ</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Antón+SC%22">Antón SC</searchLink><br /><searchLink fieldCode="AU" term="%22Brent+LJN%22">Brent LJN</searchLink><br /><searchLink fieldCode="AU" term="%22Higham+JP%22">Higham JP</searchLink><br /><searchLink fieldCode="AU" term="%22Martínez+MI%22">Martínez MI</searchLink><br /><searchLink fieldCode="AU" term="%22Melin+AD%22">Melin AD</searchLink><br /><searchLink fieldCode="AU" term="%22Montague+MJ%22">Montague MJ</searchLink><br /><searchLink fieldCode="AU" term="%22Platt+ML%22">Platt ML</searchLink><br /><searchLink fieldCode="AU" term="%22Sallet+J%22">Sallet J</searchLink><br /><searchLink fieldCode="AU" term="%22Snyder-Mackler+N%22">Snyder-Mackler N</searchLink> – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Cayo+Biobank+Research+Unit‡%22">Cayo Biobank Research Unit‡</searchLink><br /><searchLink fieldCode="CA" term="%22Cayo+Biobank+Research+Unit%22">Cayo Biobank Research Unit</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220404511%22">Science (New York, N.Y.)</searchLink> [Science] 2026 Jun 18; Vol. 392 (6804), pp. eaea4922. <i>Date of Electronic Publication: </i>2026 Jun 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0404511 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-9203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200368075%22">00368075 </searchLink><i>NLM ISO Abbreviation: </i>Science <i>Subsets: </i>MEDLINE |
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