Intraocular delivery of crystalline sorafenib provides sustained, potent inhibition of wet age-related macular degeneration.
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| Title: | Intraocular delivery of crystalline sorafenib provides sustained, potent inhibition of wet age-related macular degeneration. |
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| Authors: | Lu H; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Rakoski AI; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA., Ri K; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zhou L; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Shi L; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Cho H; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Wu S; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Chen SS; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA., Neill AN; Department of Chemistry, The Johns Hopkins University, Baltimore, MD, USA., Catazaro J; Department of Chemistry, The Johns Hopkins University, Baltimore, MD, USA., Wong VW; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA., Yoo A; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA., Wilson DS; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA., Doloff JC; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of Materials Science and Engineering, Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Oncology, Division of Cancer Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Sidney-Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: jcdoloff@jhu.edu., Duh EJ; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: eduh@jhmi.edu. |
| Source: | Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2026 Jun 18; Vol. 397, pp. 115120. Date of Electronic Publication: 2026 Jun 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42314988 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Intraocular delivery of crystalline sorafenib provides sustained, potent inhibition of wet age-related macular degeneration. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lu+H%22">Lu H</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rakoski+AI%22">Rakoski AI</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ri+K%22">Ri K</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Shi+L%22">Shi L</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cho+H%22">Cho H</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chen+SS%22">Chen SS</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Neill+AN%22">Neill AN</searchLink>; Department of Chemistry, The Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Catazaro+J%22">Catazaro J</searchLink>; Department of Chemistry, The Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wong+VW%22">Wong VW</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yoo+A%22">Yoo A</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+DS%22">Wilson DS</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Doloff+JC%22">Doloff JC</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of Materials Science and Engineering, Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Oncology, Division of Cancer Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Sidney-Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: jcdoloff@jhu.edu.<br /><searchLink fieldCode="AU" term="%22Duh+EJ%22">Duh EJ</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: eduh@jhmi.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228607908%22">Journal of controlled release : official journal of the Controlled Release Society</searchLink> [J Control Release] 2026 Jun 18; Vol. 397, pp. 115120. <i>Date of Electronic Publication: </i>2026 Jun 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Publishers%22">Elsevier Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8607908 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4995 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201683659%22">01683659 </searchLink><i>NLM ISO Abbreviation: </i>J Control Release <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42314988 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jconrel.2026.115120 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 115120 Titles: – TitleFull: Intraocular delivery of crystalline sorafenib provides sustained, potent inhibition of wet age-related macular degeneration. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lu H – PersonEntity: Name: NameFull: Rakoski AI – PersonEntity: Name: NameFull: Ri K – PersonEntity: Name: NameFull: Zhou L – PersonEntity: Name: NameFull: Shi L – PersonEntity: Name: NameFull: Cho H – PersonEntity: Name: NameFull: Wu S – PersonEntity: Name: NameFull: Chen SS – PersonEntity: Name: NameFull: Neill AN – PersonEntity: Name: NameFull: Catazaro J – PersonEntity: Name: NameFull: Wong VW – PersonEntity: Name: NameFull: Yoo A – PersonEntity: Name: NameFull: Wilson DS – PersonEntity: Name: NameFull: Doloff JC – PersonEntity: Name: NameFull: Duh EJ IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 06 Text: 2026 Jun 18 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1873-4995 Numbering: – Type: volume Value: 397 Titles: – TitleFull: Journal of controlled release : official journal of the Controlled Release Society Type: main |
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