A report of thirteen non-conventional FLCN-mutated (renal) tumors (FMT) and a discussion of proposed diagnostic criteria, convergent FLCN/TFEB and FLCN/MITF E318K signaling, and FLCN immunohistochemistry.

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Title: A report of thirteen non-conventional FLCN-mutated (renal) tumors (FMT) and a discussion of proposed diagnostic criteria, convergent FLCN/TFEB and FLCN/MITF E318K signaling, and FLCN immunohistochemistry.
Authors: Gupta S; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: gupta.sounak@mayo.edu., Sterner RM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: sterner.rosalie@mayo.edu., Hasumi H; Department of Urology, Yokohama City University, Yokohama, Japan. Electronic address: hasumi@yokohama-cu.ac.jp., Jikuya R; Department of Urology, Yokohama City University, Yokohama, Japan; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. Electronic address: jikuya@yokohama-cu.ac.jp., Nakagawa H; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. Electronic address: hidewaki@riken.jp., Kryvenko ON; Department of Pathology and Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address: o.kryvenko@med.miami.edu., Jorda M; Department of Pathology and Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address: mjorda@med.miami.edu., Torell NR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: torell.nate@mayo.edu., Stander Z; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: stander.zinandre@mayo.edu., Colef RG; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: colef.robert@mayo.edu., Tekin B; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: tekin.burak@mayo.edu., Whaley RD; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: whaley.rumeal@mayo.edu., Hernandez LH; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: HerreraHernandez.Loren@mayo.edu., Jimenez RE; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: Jimenez.Rafael@mayo.edu., Lucas PC; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: Lucas.Peter@mayo.edu., Kipp BR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: kipp.benjamin@mayo.edu., Shen W; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: shen.wei@mayo.edu., Erickson LA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: erickson.lori@mayo.edu., Dasari S; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. Electronic address: Dasari.Surendra@mayo.edu., Cheville JC; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: cheville.john@mayo.edu.
Source: Human pathology [Hum Pathol] 2026 Jun 18; Vol. 177, pp. 106205. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: W B Saunders Country of Publication: United States NLM ID: 9421547 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8392 (Electronic) Linking ISSN: 00468177 NLM ISO Abbreviation: Hum Pathol Subsets: MEDLINE
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  Data: A report of thirteen non-conventional FLCN-mutated (renal) tumors (FMT) and a discussion of proposed diagnostic criteria, convergent FLCN/TFEB and FLCN/MITF E318K signaling, and FLCN immunohistochemistry.
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  Data: <searchLink fieldCode="AU" term="%22Gupta+S%22">Gupta S</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: gupta.sounak@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Sterner+RM%22">Sterner RM</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: sterner.rosalie@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Hasumi+H%22">Hasumi H</searchLink>; Department of Urology, Yokohama City University, Yokohama, Japan. Electronic address: hasumi@yokohama-cu.ac.jp.<br /><searchLink fieldCode="AU" term="%22Jikuya+R%22">Jikuya R</searchLink>; Department of Urology, Yokohama City University, Yokohama, Japan; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. Electronic address: jikuya@yokohama-cu.ac.jp.<br /><searchLink fieldCode="AU" term="%22Nakagawa+H%22">Nakagawa H</searchLink>; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. Electronic address: hidewaki@riken.jp.<br /><searchLink fieldCode="AU" term="%22Kryvenko+ON%22">Kryvenko ON</searchLink>; Department of Pathology and Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address: o.kryvenko@med.miami.edu.<br /><searchLink fieldCode="AU" term="%22Jorda+M%22">Jorda M</searchLink>; Department of Pathology and Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address: mjorda@med.miami.edu.<br /><searchLink fieldCode="AU" term="%22Torell+NR%22">Torell NR</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: torell.nate@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Stander+Z%22">Stander Z</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: stander.zinandre@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Colef+RG%22">Colef RG</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: colef.robert@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Tekin+B%22">Tekin B</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: tekin.burak@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Whaley+RD%22">Whaley RD</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: whaley.rumeal@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Hernandez+LH%22">Hernandez LH</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: HerreraHernandez.Loren@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Jimenez+RE%22">Jimenez RE</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: Jimenez.Rafael@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Lucas+PC%22">Lucas PC</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: Lucas.Peter@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Kipp+BR%22">Kipp BR</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: kipp.benjamin@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Shen+W%22">Shen W</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: shen.wei@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Erickson+LA%22">Erickson LA</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: erickson.lori@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Dasari+S%22">Dasari S</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. Electronic address: Dasari.Surendra@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Cheville+JC%22">Cheville JC</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: cheville.john@mayo.edu.
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  Data: <searchLink fieldCode="JN" term="%229421547%22">Human pathology</searchLink> [Hum Pathol] 2026 Jun 18; Vol. 177, pp. 106205. <i>Date of Electronic Publication: </i>2026 Jun 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W+B+Saunders%22">W B Saunders </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9421547 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-8392 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200468177%22">00468177 </searchLink><i>NLM ISO Abbreviation: </i>Hum Pathol <i>Subsets: </i>MEDLINE
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