Early oligodendrocyte dysfunction signature in Alzheimer's disease: Insights from DNA methylomics and transcriptomics.

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Title: Early oligodendrocyte dysfunction signature in Alzheimer's disease: Insights from DNA methylomics and transcriptomics.
Authors: Fodder K; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK., Smith HMG; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK., Yaman U; UK Dementia Research Institute, London, UK., Piras IS; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA., Murthy M; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK., Hardy J; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; UK Dementia Research Institute, London, UK., Lashley T; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK., de Silva R; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, UK., Salih DA; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; UK Dementia Research Institute, London, UK., Bettencourt C; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK. c.bettencourt@ucl.ac.uk.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jun 18. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5578
DOI:10.1038/s41380-026-03686-1