Critical role of high-dose Astragalus in Buyang Huanwu Decoction for enhancing neurovascular coupling in a Qi Deficiency and Blood Stasis animal model.
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| Title: | Critical role of high-dose Astragalus in Buyang Huanwu Decoction for enhancing neurovascular coupling in a Qi Deficiency and Blood Stasis animal model. |
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| Authors: | Hu K; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130012, Jilin, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Yang J; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Wei G; Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Chinese Medicine & Pharmaceutical Science, Nanning, 530022, China., Zhao Y; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Chu S; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Li L; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Wang S; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Qu S; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Chen L; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Zhang Y; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Yan X; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China., Zhang Z; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China. zhangzhao@imm.ac.cn.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. zhangzhao@imm.ac.cn., Chen N; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130012, Jilin, China. chennh@imm.ac.cn.; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China. chennh@imm.ac.cn.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. chennh@imm.ac.cn., He W; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China. hewb@sxtcm.edu.cn. |
| Source: | Chinese medicine [Chin Med] 2026 Jun 18; Vol. 21 (1). Date of Electronic Publication: 2026 Jun 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101265109 Publication Model: Electronic Cited Medium: Print ISSN: 1749-8546 (Print) Linking ISSN: 17498546 NLM ISO Abbreviation: Chin Med Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42316268 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Critical role of high-dose Astragalus in Buyang Huanwu Decoction for enhancing neurovascular coupling in a Qi Deficiency and Blood Stasis animal model. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hu+K%22">Hu K</searchLink>; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130012, Jilin, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Wei+G%22">Wei G</searchLink>; Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Chinese Medicine & Pharmaceutical Science, Nanning, 530022, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Chu+S%22">Chu S</searchLink>; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Qu+S%22">Qu S</searchLink>; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Yan+X%22">Yan X</searchLink>; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China. zhangzhao@imm.ac.cn.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. zhangzhao@imm.ac.cn.<br /><searchLink fieldCode="AU" term="%22Chen+N%22">Chen N</searchLink>; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, 130012, Jilin, China. chennh@imm.ac.cn.; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China. chennh@imm.ac.cn.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. chennh@imm.ac.cn.<br /><searchLink fieldCode="AU" term="%22He+W%22">He W</searchLink>; Shanxi Key Laboratory of Integrative Systemic Regulation for Qi-Blood Homeostasis, National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030024, China. hewb@sxtcm.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101265109%22">Chinese medicine</searchLink> [Chin Med] 2026 Jun 18; Vol. 21 (1). <i>Date of Electronic Publication: </i>2026 Jun 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101265109 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1749-8546 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217498546%22">17498546 </searchLink><i>NLM ISO Abbreviation: </i>Chin Med <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42316268 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13020-026-01443-8 Languages: – Code: eng Text: English Titles: – TitleFull: Critical role of high-dose Astragalus in Buyang Huanwu Decoction for enhancing neurovascular coupling in a Qi Deficiency and Blood Stasis animal model. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hu K – PersonEntity: Name: NameFull: Yang J – PersonEntity: Name: NameFull: Wei G – PersonEntity: Name: NameFull: Zhao Y – PersonEntity: Name: NameFull: Chu S – PersonEntity: Name: NameFull: Li L – PersonEntity: Name: NameFull: Wang S – PersonEntity: Name: NameFull: Qu S – PersonEntity: Name: NameFull: Chen L – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Yan X – PersonEntity: Name: NameFull: Zhang Z – PersonEntity: Name: NameFull: Chen N – PersonEntity: Name: NameFull: He W IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 06 Text: 2026 Jun 18 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 1749-8546 Numbering: – Type: volume Value: 21 – Type: issue Value: 1 Titles: – TitleFull: Chinese medicine Type: main |
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