Intrathecal (G4C2)149 delivery in C9orf72-deficient mice yields mild motor dysfunction and ALS/FTD pathological hallmarks.
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| Title: | Intrathecal (G |
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| Authors: | Russell KA; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA., Shahrabi AA; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA., Akerman SC; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Byrne MD; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA., Rothstein JD; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Trotti D; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA., Jensen BK; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA., Haeusler AR; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA. aaron.haeusler@jefferson.edu.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA. aaron.haeusler@jefferson.edu. |
| Source: | Acta neuropathologica communications [Acta Neuropathol Commun] 2026 Jun 18. Date of Electronic Publication: 2026 Jun 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42316301 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Intrathecal (G<subscript>4</subscript>C<subscript>2</subscript>)<subscript>149</subscript> delivery in C9orf72-deficient mice yields mild motor dysfunction and ALS/FTD pathological hallmarks. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Russell+KA%22">Russell KA</searchLink>; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.<br /><searchLink fieldCode="AU" term="%22Shahrabi+AA%22">Shahrabi AA</searchLink>; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.<br /><searchLink fieldCode="AU" term="%22Akerman+SC%22">Akerman SC</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Byrne+MD%22">Byrne MD</searchLink>; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.<br /><searchLink fieldCode="AU" term="%22Rothstein+JD%22">Rothstein JD</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Trotti+D%22">Trotti D</searchLink>; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.<br /><searchLink fieldCode="AU" term="%22Jensen+BK%22">Jensen BK</searchLink>; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA.<br /><searchLink fieldCode="AU" term="%22Haeusler+AR%22">Haeusler AR</searchLink>; Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA. aaron.haeusler@jefferson.edu.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, 19107, USA. aaron.haeusler@jefferson.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101610673%22">Acta neuropathologica communications</searchLink> [Acta Neuropathol Commun] 2026 Jun 18. <i>Date of Electronic Publication: </i>2026 Jun 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101610673 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2051-5960 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220515960%22">20515960 </searchLink><i>NLM ISO Abbreviation: </i>Acta Neuropathol Commun <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42316301 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s40478-026-02341-8 Languages: – Code: eng Text: English Titles: – TitleFull: Intrathecal (G4C2)149 delivery in C9orf72-deficient mice yields mild motor dysfunction and ALS/FTD pathological hallmarks. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Russell KA – PersonEntity: Name: NameFull: Shahrabi AA – PersonEntity: Name: NameFull: Akerman SC – PersonEntity: Name: NameFull: Byrne MD – PersonEntity: Name: NameFull: Rothstein JD – PersonEntity: Name: NameFull: Trotti D – PersonEntity: Name: NameFull: Jensen BK – PersonEntity: Name: NameFull: Haeusler AR IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 06 Text: 2026 Jun 18 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2051-5960 Titles: – TitleFull: Acta neuropathologica communications Type: main |
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